Concentrate for medical solutions, production thereof and use thereof in dialysis
First Claim
1. A concentrate for producing a medical solution, wherein the concentrate comprises at least three spatially separated parts, wherein the first part comprises magnesium carbonate, anhydrous calcium chloride, and a physiologically acceptable acid selected from the group consisting of citric acid, malic acid, fumaric acid, isocitric acid, succinic acid and oxalic acid, and is suitable for use as the medical solution upon addition of an aqueous medium.
1 Assignment
0 Petitions
Accused Products
Abstract
The present invention relates to a novel dry concentrate for producing medical solutions, more particularly dialysis solutions, which comprises electrolyte components, buffer components and an osmotic agent, wherein the concentrate comprises magnesium carbonate instead of magnesium chloride. The use of magnesium carbonate as an electrolyte prevents the formation of slurries. By providing anhydrous glucose as an osmotic agent, and by optionally spatially separating this osmotic agent from other components, the occurrence of caking of the concentrate is additionally avoided. The occurrence of caking is further reduced by providing the buffer component sodium bicarbonate together with sodium chloride separate from all other components. The concentrate of the present invention is particularly suitable for use in multi-chamber container bag systems. The concentrate of the present invention exhibits good dissolution behavior and improved storage stability.
-
Citations
26 Claims
- 1. A concentrate for producing a medical solution, wherein the concentrate comprises at least three spatially separated parts, wherein the first part comprises magnesium carbonate, anhydrous calcium chloride, and a physiologically acceptable acid selected from the group consisting of citric acid, malic acid, fumaric acid, isocitric acid, succinic acid and oxalic acid, and is suitable for use as the medical solution upon addition of an aqueous medium.
- 16. A concentrate for producing a medical solution, wherein the concentrate comprises at least three spatially separated parts, wherein the first part comprises magnesium carbonate and/or anhydrous calcium chloride, the second part comprises glucose and the third part comprises sodium bicarbonate, and wherein the concentrate is suitable for use as the medical solution upon addition of an aqueous medium.
Specification