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Composite hydrogel drug delivery systems

  • US 9,254,267 B2
  • Filed: 07/11/2008
  • Issued: 02/09/2016
  • Est. Priority Date: 08/14/1998
  • Status: Active Grant
First Claim
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1. A method of making a gel, the method comprising reacting one or more hydrophilic, synthetic macromers through covalent reactions to form a continuous, bioabsorbable, synthetic, covalently crosslinked hydrogel matrix in the presence of a hydrophobic material and a therapeutic agent, with a plurality of non-gaseous hydrophobic domains being formed from the hydrophobic material and dispersed in the continuous hydrogel matrix, with the therapeutic agent being associated with the hydrophobic domains.

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