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Mammalian receptors as targets for antibody and active vaccination therapy against mold infections

  • US 9,259,467 B2
  • Filed: 12/23/2013
  • Issued: 02/16/2016
  • Est. Priority Date: 09/01/2009
  • Status: Active Grant
First Claim
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1. A method of treating mucormycosis comprising administering to a human subject having mucormycosis a composition, wherein the composition comprises a therapeutically effective amount of an isolated antibody or an antibody fragment thereof that specifically binds the human glucose-regulated protein, 78 kD polypeptide (GRP78) or an antigenic fragment thereof in said human subject, wherein said mucormycosis is caused by a Rhizopus species.

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