Bag for a circuit of a biological liquid treatment installation

• US 9,259,687 B2
• Filed: 05/08/2013
• Issued: 02/16/2016
• Est. Priority Date: 06/23/2010
• Status: Active Grant

• Current Assignee: EMD Millipore Corporation (Merck & Co., Inc.)
• Original Assignee: EMD Millipore Corporation (Merck & Co., Inc.)
• Inventors: Weissenbach, Jean-Louis, Cirou, Sebastien
• Primary Examiner(s): Therkorn, Ernest G
• Application Number:
  US13/889,616
• Publication Number:
  US 20130240065A1
• Time in Patent Office: 1,014 Days
• Field of Search: 210/635, 210/656, 210/198.2, 210/321.6, 210/321.72, 210/541, 137/343, 137/377
• US Class Current: 1/1
• CPC Class Codes: B01D 2313/105 Supply manifolds
• CPC Class Codes: B01D 2313/125 Discharge manifolds
• CPC Class Codes: B01D 2313/13 Specific connectors
• CPC Class Codes: B01D 2313/18 Specific valves
• CPC Class Codes: B01D 2313/58 Parts of membrane modules specifically adapted for single use
• CPC Class Codes: B01D 2313/903 Integrated control or detection device
• CPC Class Codes: B01D 2315/10 Cross-flow filtration
• CPC Class Codes: B01D 61/20 Accessories; Auxiliary operations
• CPC Class Codes: B01D 63/00 Apparatus in general for separation processes using semi-permeable membranes
• CPC Class Codes: Y10T 137/6851 With casing, support, protector or static constructional installations
• CPC Class Codes: Y10T 137/8593 Systems

Abstract

The invention concerns a bag comprising a first conduit (13C) which extends longitudinally between a flow pump connector (11C) emerging on a first side (68) and a tangential filter connector (11M) emerging on a second side (69); a second conduit (13B) which extends longitudinally from a first side of said conduit (13C) between a supply container connector (11B) emerging on said first side (68), and another tangential flow connector (11N) emerging on said second side (69); a third conduit (13H) which extends from a second side of said conduit (13C), starting at a collecting container connector (11J), until it enters said first conduit (13C); and a fourth conduit (13A) which extends from the first side of said conduit (13C), starting at a transfer pump connector (11A), until it enters said second conduit (13B).

Claims

1. A device for an installation for biological liquid treatment by tangential filtration, comprising a circuit comprising:

a bag provided with a plurality of connectors and a network for conveying liquid between said connectors, said conveying network being formed by a plurality of conduits, the bag further comprising two flexible films fastened to each other, said conduits being formed between said flexible films;

a press comprising a first shell and a second shell mounted on said first shell, said first shell and second shell cooperating with said bag to form the conduits of said conveying network between said flexible films, by clamping said bag between said first shell and said second shell; and

a plurality of valves;

a first conduit extending longitudinally between a flow pump connector emerging on a first side of said bag and a tangential filter connector emerging on a second side of said bag which is an opposite side to said first side;

a second conduit extending longitudinally from a first side of said conduit between a supply container connector emerging on said first side of said bag, and another tangential filter connector emerging on said second side of said bag which is an opposite side to said first side;

a third conduit extending from a second side of said conduit, which is an opposite side to said first side of said conduit, starting at a collecting container connector, until it enters said first conduit;

a fourth conduit extending from the first side of said conduit, starting at a transfer pump connector, until it enters said second conduit; and

at least a first valve being situated on said first conduit, at least a second valve being situated on said second conduit, a third valve being situated on said third conduit, and a fourth valve being situated on said fourth conduit.

2. A device according to claim 1, wherein the bag comprises a fifth conduit connected to a transfer pump connector, and a sixth conduit extending from a source container connector until it enters said fifth conduit, and the device comprises a fifth valve situated on said fifth conduit and a sixth valve situated on said sixth conduit.

3. A device according to claim 2, wherein the bag comprises at least a seventh conduit which extends from a buffer and/or cleaning container connector until it enters said fifth conduit, and the device comprises at least a seventh valve situated on said seventh conduit.

4. A device according to claim 3, wherein the bag comprises an eighth conduit which extends between an air filter connector and a rinsing container connector, said fifth conduit entering said eighth conduit, and the device comprises at least one eighth valve situated on said eighth conduit.

5. A device according to claim 4, wherein the bag comprises at least a ninth conduit which extends between a tangential filter connector and a waste container connector, and the device comprises at least a ninth valve situated on said ninth conduit.

6. A device according to claim 1, further comprising a pressure sensor situated on at least one said conduit.