Measuring method of life activity, measuring device of life activity, transmission method of life activity detection signal, or service based on life activity information

• US 9,265,425 B2
• Filed: 11/07/2012
• Issued: 02/23/2016
• Est. Priority Date: 11/11/2011
• Status: Active Grant

• Current Assignee: Hideo Ando
• Original Assignee: Hideo Ando
• Inventors: Ando, Hideo
• Primary Examiner(s): Cattungal, Sanjay
• Application Number:
  US13/670,814
• Publication Number:
  US 20130123639A1
• Time in Patent Office: 1,203 Days
• Field of Search: 600407-480
• US Class Current: 1/1
• CPC Class Codes: A61B 2562/0242 for varying or adjusting the optical path length in the tissue
• CPC Class Codes: A61B 2576/00 Medical imaging apparatus involving image processing or analysis A61B1/00009, A61B6/52 and A61B8/52 take precedence; image processing per se G06T; details of algorithms for analysing medical images G06T7/0012
• CPC Class Codes: A61B 5/0013 Medical image data A61B1/00011, A61B6/56, A61B8/56 take precedence
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/0068 Confocal scanning
• CPC Class Codes: A61B 5/0075 by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy A61B5/0071 takes precedence
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: A61B 5/40 Detecting, measuring or recording for evaluating the nervous system A61B5/4806, A61B5/4821, A61B5/4824 take precedence
• CPC Class Codes: A61B 5/4041 Evaluating nerves condition
• CPC Class Codes: A61B 5/4519 Muscles A61B5/389, A61B5/224 take precedence
• CPC Class Codes: A61B 5/486 Bio-feedback A61B5/375 takes precedence
• CPC Class Codes: A61B 5/7228 Signal modulation applied to the input signal sent to patient or subject; demodulation to recover the physiological signal modulation H03C
• CPC Class Codes: A61B 5/7246 using correlation, e.g. template matching or determination of similarity
• CPC Class Codes: G01P 13/00 Indicating or recording presence, absence, or direction, of movement electric switches H01H; counting moving objects G06M7/00

Abstract

According to a measuring method or a control method of life activity, a life object is illuminated with an electromagnetic wave including a wavelength in a designated waveband, and a characteristic in a local area of the life object is detected, or a life activity thereof is controlled. This “local area” is an area constituted by one or more cells. The “designated waveband” is defined based on any one of the following phenomena:

• [1] transition energy between a ground state of a vibration mode newly occurring between atoms in a constituent molecule of a cell membrane and a plurality of excited states;
• [2] transition energy between vibration modes occurring between specific atoms in a molecule corresponding to the activity of the life object or the change thereof; and
• [3] a specific chemical shift value in Nuclear Magnetic Resonance.

Claims

1. A non-invasive method applied to a life object, comprising:

irradiating the life object with a first electromagnetic wave having a prescribed wavelength, the prescribed wavelength being included in a range from 1.028 μ

m to 2.50 μ

m;

setting a position of a detected area related to a depth below a surface of the life object; and

detecting a signal relating to a second electromagnetic wave, the second electromagnetic wave having a wavelength same as the prescribed wavelength, the second electromagnetic wave being obtained from the detected area, and at least a part of the second electromagnetic wave being condensed out of the life object; and

detecting neural activity in the life object based on the detected signal, the neural activity relating to a nerve impulse of neuron.

2. The method according to claim 1, wherein the position of the detected area is optically detected.

3. The method according to claim 2, wherein the position of the detected area is detected with a third electromagnetic wave obtained from the life object.

4. The method according to claim 3, wherein the position of the detected area is detected using an image pattern formed by the third electromagnetic wave.

5. The method according to claim 4, wherein the position of the detected area is detected using the image pattern formed by the third electromagnetic wave and a pattern matching method.

6. The method according to claim 3, wherein the position of the detected area is detected using trigonometry.

7. The method according to claim 1, wherein the first electromagnetic wave is condensed toward the life object.

8. The method according to claim 1, further comprising:

measuring muscular activity in vivo.

9. The method according to claim 1, further comprising:

controlling life activity in the life object.

10. The method according to claim 1, further comprising:

transmitting information related to the detected signal.

11. The method according to claim 1, further comprising:

providing a service based on the detected signal.

12. A non-invasive method applied to a life object, comprising:

irradiating the life object with a first electromagnetic wave having a prescribed wavelength, the prescribed wavelength being included in a range from 1.028 μ

m to 2.50 μ

m;

setting a position of a detected area related to a depth below a surface of the life object; and

detecting a signal relating to a second electromagnetic wave, the second electromagnetic wave having a wavelength same as the prescribed wavelength, the second electromagnetic wave being obtained from the detected area, and at least a part of the second electromagnetic wave being condensed out of the life object; and

detecting neural activity in the life object based on the detected signal, the neural activity relating to a signal transmission through an axon of a neuron.

13. The method according to claim 12, wherein the position of the detected area is optically detected with a third electromagnetic wave obtained form the life object.

14. The method according to claim 13, wherein the position of the detected area is detected using an image pattern formed by the third electromagnetic wave.

15. The method according to claim 12, further comprising:

measuring muscular activity in vivo.

16. The method according to claim 12, further comprising:

controlling life activity in the life object.

17. The method according to claim 12, further comprising:

transmitting information related to the detected signal.

18. The method according to claim 12, further comprising:

providing service based on the detected signal.