Ablation instruments and related methods

• US 9,265,563 B2
• Filed: 02/22/2007
• Issued: 02/23/2016
• Est. Priority Date: 02/22/2006
• Status: Active Grant

• Current Assignee: Custom Medical Applications, Inc.
• Original Assignee: Custom Medical Applications, Inc.
• Inventors: Racz, N. Sandor, Ruiz-Lopez, Ricardo
• Primary Examiner(s): Schmidt, Emily
• Assistant Examiner(s): PENG, LAUREN MICHELE
• Application Number:
  US12/224,321
• Publication Number:
  US 20090187179A1
• Time in Patent Office: 3,288 Days
• Field of Search: 606/33, 606/41, 606/42, 606 45- 50, 607/98, 607/99, 607/101, 607/102, 607/115, 607/116, 607/122, 607154-156, 604/96.01
• US Class Current: 1/1
• CPC Class Codes: A61B 18/1206 Generators therefor
• CPC Class Codes: A61B 18/14 Probes or electrodes therefor
• CPC Class Codes: A61B 18/1477 Needle-like probes
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00702 Power or energy
• CPC Class Codes: A61B 2018/00791 Temperature
• CPC Class Codes: A61B 2018/00875 Resistance or impedance
• CPC Class Codes: A61B 2018/1407 Loop
• CPC Class Codes: A61B 2018/1425 Needle
• CPC Class Codes: A61B 2018/144 Wire
• CPC Class Codes: A61B 2018/1467 using more than two electrodes on a single probe

Abstract

An ablation instrument including a body and an ablating member is provided. The body includes a distal end and a surface with the ablating member coupled toward the distal end of the body. The ablating member includes a lesion wire extending through and along a portion of the surface of the body for creating lesions in a target tissue while the body serves to isolate surrounding tissue from the target tissue. A method of ablating a target area is also provided.

Claims

1. An ablation instrument comprising:

a rigid body having a distal end, an outer side surface, and at least two holes formed in the outer side surface of the body; and

an ablating member coupled toward the distal end of the body, the ablating member comprising a lesion wire having an external portion extending through each hole of the at least two holes formed in the outer side surface of the body and extending externally along the outer side surface of the body in substantial alignment with an axial direction of the body spaced from the outer side surface of the body, the lesion wire for creating lesions in a target tissue and wherein the body isolates surrounding tissue from the target tissue, wherein an entirety of the lesion wire including the external portion of the lesion wire extending through each hole of the at least two holes formed in the outer side surface of the body and extending externally along the outer side surface of the body is fixed relative to the rigid body such that the entirety of the lesion wire is non-deployable from the rigid body and non-retractable into the rigid body.

2. The ablation instrument of claim 1, wherein the body is substantially cylindrical and relatively slender in an axial direction, and wherein the majority of the portion of the lesion wire extending externally along the outer side surface of the body extends along the body directly above the outer side surface of the body.

3. The ablation instrument of claim 1, wherein the body is made from a conductive material and the lesion wire of the ablating member is insulated within the body.

4. The ablation instrument of claim 1, wherein a portion of the body forming each hole of the least two holes comprises an insulative coating surrounding a portion of the lesion wire extending therethrough to electrically isolate the lesion wire from the body.

5. The ablation instrument of claim 1, further comprising a second lesion wire circumferentially spaced from the lesion wire, the second lesion wire having a portion extending through the outer side surface of the body and extending externally along the outer side surface of the body in substantial alignment with an axial direction of the body spaced from the outer side surface of the body.

6. The ablation instrument of claim 1, wherein the lesion wire is selected for radiating energy in the radio frequency (RF) electromagnetic spectrum.

7. The ablation instrument of claim 6, further comprising an energy source electrically coupled to the lesion wire and selected from the group consisting of RF, microwave radiation, an inductively coupled RF fields, ultrasound, shortwave, and thermal conductive wire.

8. The ablation instrument of claim 1, further comprising a thermal sensor for measuring at least one of an impedance about the thermal sensor and a temperature about the thermal sensor.

9. The ablation instrument of claim 1, wherein a majority of the portion of the lesion wire extending externally along the outer side surface of the body extends substantially parallel to axial direction of the body.

10. The ablation instrument of claim 1, wherein the body further comprises one of a bent and arcuate distal tip.

11. The ablation instrument of claim 1, wherein the lesion wire of the ablating member extends across the body through at least one infusion port to an electrical coupling system.

12. The ablation instrument of claim 1, further comprising a guidance system.

13. The ablation instrument of claim 1, further comprising a thermal sensor means for measuring impedance or temperature.

14. The ablation instrument of claim 1, further comprising a guidance means.

15. A method of ablating a target tissue, comprising:

inserting the ablation instrument of claim 1 into a patient;

orienting the ablating member of the ablation instrument about a target tissue;

at least partially isolating surrounding tissue from the target tissue with the body of the ablation instrument; and

ablating the target tissue.

16. The method of claim 15, further comprising measuring at least one of temperature of the ablating member, temperature of the target area, and impedance of the target area.

17. The method of claim 16, further comprising stopping ablating the target tissue when the thermal sensor measures a set point temperature and/or impedance.

18. The method of claim 15, further comprising orienting a thermal sensor about a sensitive area of the patient to monitor the temperature and/or the impedance of the sensitive area.

19. The method of claim 15, wherein inserting an ablation instrument with a body and an ablating member into a patient is for a procedure comprising at least one of rhizotomy, pulmonary ablation, organ ablation, and nerve end ablation.

20. An ablation instrument comprising:

a body having a distal end and an outer side surface; and

an ablating member coupled toward the distal end of the body, the ablating member comprising a lesion wire having a fixed external portion coupled to a portion of the body, an entirety of the lesion wire and the fixed external portion of the lesion that is external to the body being non-deployable and non-retractable relative to the body, the fixed external portion extending through the outer side surface of the body, extending externally along the outer side surface of the body in a direction substantially parallel to an axial direction of the body, and extending back through the outer side surface of the body, the lesion wire for creating lesions in a target tissue.

21. The ablation instrument of claim 20, further comprising a thermal sensor for measuring at least one of an impedance about the thermal sensor and a temperature about the thermal sensor.