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Method and system for improved estimation of time of left ventricular pacing with respect to intrinsic right ventricular activation in cardiac resynchronization therapy

  • US 9,265,954 B2
  • Filed: 07/26/2013
  • Issued: 02/23/2016
  • Est. Priority Date: 07/26/2013
  • Status: Active Grant
First Claim
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1. A computer-implemented method of cardiac pacing comprising:

  • determining a baseline rhythm, the baseline rhythm includes a baseline atrial event and a baseline right ventricular (RV) event from an implanted cardiac lead or a leadless device, a pre-excitation interval determined from the baseline atrial event and the baseline RV event, and a plurality of cardiac electrical activation times determined from a plurality of body-surface electrodes;

    determining whether a time interval measured from an atrial event to a RV event is disparate from another time interval measured from the atrial event to an earliest RV activation time of the plurality of activation times;

    applying a correction factor to the pre-excitation interval to obtain a corrected pre-excitation interval in response to determining the time interval measured from the atrial event to the RV event is disparate from the time interval measured from the atrial event to the earliest RV activation time; and

    configuring the processor to signal the pulse generator to deliver electrical stimuli to a left ventricle (LV) using the corrected pre-excitation interval before the RV sensing time.

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