Composite sensor assemblies for single use bioreactors
First Claim
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1. A composite sensor assembly for use with a polymeric bioprocess vessel, said sensor assembly comprising:
- i) a port comprising a high surface tension thermoplastic having a hollow portion and a base plate portion, at least said base plate portion comprising a polymer fusibly sealable to the bioprocess vessel at a hole in the wall thereof; and
ii) a polymeric monitoring sensor unit including at least one electrical, and/or chemical and/or optical measurement component, said sensor unit including a base portion and being generally dish shaped and sized to fit inside the bore of the hollow portion of said port, and being adhesively retained therein, said port providing the monitoring sensor unit measurement component or components with access to the contents of said bioreactor vessel, which component or components include means for providing incoming optical and/or electrical signals and means for collecting and transmitting measurement signals emitted by the components.
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Abstract
A composite sensor assembly for monitoring bio-processes which is suitable for use with a polymeric bioprocess vessel or with downstream equipment, and comprises:
- i) a port comprising a high surface tension thermoplastic having a hollow tubular portion and a base plate portion, the base plate portion being fusibly sealable to the bioreactor vessel at a hole in the wall thereof;
- ii) a generally opaque polymeric monitoring sensor assembly including electrical, and/or optical measurement components. The sensor assembly fits inside the bore of the hollow tubular portion of the port, and is adhesively retained therein.
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Citations
19 Claims
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1. A composite sensor assembly for use with a polymeric bioprocess vessel, said sensor assembly comprising:
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i) a port comprising a high surface tension thermoplastic having a hollow portion and a base plate portion, at least said base plate portion comprising a polymer fusibly sealable to the bioprocess vessel at a hole in the wall thereof; and ii) a polymeric monitoring sensor unit including at least one electrical, and/or chemical and/or optical measurement component, said sensor unit including a base portion and being generally dish shaped and sized to fit inside the bore of the hollow portion of said port, and being adhesively retained therein, said port providing the monitoring sensor unit measurement component or components with access to the contents of said bioreactor vessel, which component or components include means for providing incoming optical and/or electrical signals and means for collecting and transmitting measurement signals emitted by the components. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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Specification