Method for integrated sample acquisition and analyte measurement device
First Claim
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1. A method of electrochemically determining a concentration of an analyte in blood, comprising:
- manually rubbing a region of skin other than the fingertips for at least 1 second,after manually rubbing, lancing the region of skin to provide no more than 1 microliter of blood sample at the region of skin;
contacting a sensor coupled to a meter to the blood sample to transport the blood sample to a sample chamber of the sensor; and
electrochemically determining the concentration of the analyte in the blood sample using the sensor and meter, wherein the analyte concentration is at least 10% nearer a concentration determined from blood obtained from a fingertip than a determination of the concentration of analyte from blood obtained from the region of skin without manually rubbing.
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Abstract
A region of skin, other than the fingertips, is stimulated. After stimulation, an opening is created in the skin (e.g., by lancing the skin) to cause a flow of body fluid from the region. At least a portion of this body fluid is transported to a testing device where the concentration of analyte (e.g., glucose) in the body fluid is then determined. It is found that the stimulation of the skin provides results that are generally closer to the results of measurements from the fingertips, the traditional site for obtaining body fluid for analyte testing.
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Citations
14 Claims
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1. A method of electrochemically determining a concentration of an analyte in blood, comprising:
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manually rubbing a region of skin other than the fingertips for at least 1 second, after manually rubbing, lancing the region of skin to provide no more than 1 microliter of blood sample at the region of skin; contacting a sensor coupled to a meter to the blood sample to transport the blood sample to a sample chamber of the sensor; and electrochemically determining the concentration of the analyte in the blood sample using the sensor and meter, wherein the analyte concentration is at least 10% nearer a concentration determined from blood obtained from a fingertip than a determination of the concentration of analyte from blood obtained from the region of skin without manually rubbing. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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Specification