Implantable devices for subchondral treatment of joint pain

• US 9,271,835 B2
• Filed: 12/17/2013
• Issued: 03/01/2016
• Est. Priority Date: 11/20/2009
• Status: Active Grant

• Current Assignee: Zimmer Knee Creations, Inc. (Zimmer Biomet Holdings, Inc.)
• Original Assignee: Zimmer Knee Creations, Inc. (Zimmer Biomet Holdings, Inc.)
• Inventors: Bagga, Charanpreet S., Hanson, Shaun B., Mandeen, Christopher D., Simpson, Michael J., Cohen, Steven B., Leinberry, Charles F., Sharkey, Peter F.
• Primary Examiner(s): Stewart, Jason-Dennis
• Application Number:
  US14/109,368
• Publication Number:
  US 20140107781A1
• Time in Patent Office: 805 Days
• Field of Search: 606300-321, 623/16.11, 623/18.11
• US Class Current: 1/1
• CPC Class Codes: A61B 17/68 Internal fixation devices , including fasteners and spinal fixators, even if a part thereof projects from the skin bone staples A61B17/0642
• CPC Class Codes: A61B 17/7098 wherein the implant is permeable or has openings, e.g. fenestrated screw hollow surgical screws A61B17/864
• CPC Class Codes: A61B 17/8615 at the central region of the screw head
• CPC Class Codes: A61B 17/863 with thread interrupted or changing its form along shank, other than constant taper
• CPC Class Codes: A61B 17/864 hollow, e.g. with socket or cannulated
• CPC Class Codes: A61B 17/8875 Screwdrivers, spanners or wrenches
• CPC Class Codes: A61B 17/8897 Guide wires or guide pins
• CPC Class Codes: A61F 2/2846 Support means for bone substitute or for bone graft implants, e.g. membranes or plates for covering bone defects nets or sleeves applied to surface of endoprostheses A61F2/30907; bone plates A61B17/80; bone regeneration in dental surgery A61C8/0006

Abstract

Devices and associated methods are disclosed for treating bone, and particularly bone tissue at the joints. Disclosed are implantable devices that can be used either alone or in combination with this augmentation or hardening material for the repair of bone defects and which are particularly suited for use at the joints, and even more particularly suited for use at the subchondral bone level.

Claims

1. A method of treating a bone defect, comprising:

providing or obtaining a first implantable device for insertion into bone, the first implantable device comprising an elongate body extending between a first, leading end and a second, trailing end, the second end including a tool-receiving portion for receiving a tool, the elongate body including a central canal for receiving a flowable material, and having one or more channels in fluid communication with the central canal, the channels being located along one side of the elongate body;

providing or obtaining a second implantable device for insertion into bone, the second implantable device comprising an elongate body extending between a first, leading end and a second, trailing end, the second end including a tool-receiving portion for receiving a tool, the elongate body including a central canal for receiving a flowable material, and having one or more channels in fluid communication with the central canal, the channels being located along one side of the elongate body;

implanting the first and second implantable devices into a subchondral level of a bone, in a spaced apart and generally parallel configuration, such that the one or more channels of each device are oriented towards each other; and

injecting a flowable material into at least one of the implantable devices.

2. The method of claim 1, further including allowing the flowable material to extrude out of one implantable device and into the one or more channels of the other implantable device.

3. The method of claim 1, wherein implanting the first and second implantable devices into a subchondral level of a bone includes preserving an articular surface of the bone.

4. The method of claim 1, wherein the flowable material is a bone cement, bone graft material, biologic agent, osteoconductive agent, osteoinductive agent, or osteogenic agent.

5. The method of claim 1, wherein the elongate bodies of the first and second implantable devices are at least partially threaded.

6. The method of claim 1, wherein implanting the first and second implantable devices into a subchondral level of a bone comprises rotating the first and second implantable devices in a first direction.

7. The method of claim 6, further comprising removing the first and second implantable devices by rotating the first and second implantable devices in a second direction opposite to the first direction.

8. The method of claim 1, wherein the tool is an insertion tool, an injection needle, or a catheter.

9. The method of claim 1, comprising injecting the flowable material into the first implantable device and the second implantable device.

10. The method of claim 1, wherein the flowable material is injected into the first implantable device and allowed to extrude out of the one or more channels of the first implantable device and into the one or more channels of the second implantable device.

11. The method of claim 1, wherein the elongate bodies of the first and second implantable devices each include a depressed, cutaway portion for containing the area where the flowable material can extrude, the one or more channels residing within the depressed, cutaway portion.

12. The method of claim 1, wherein the flowable material is injected into at least one of the implantable devices with an injection tool having a hollow shaft insertable into the central canal of the implantable device, the injection tool including one or more channels configured to align with one or more channels of the implantable device to allow extrusion of the flowable material out of the injection tool and through the implantable device.

13. A method of treating a subchondral bone defect of a bone, comprising:

providing or obtaining an implantable device for insertion into bone, the implantable device comprising an elongate body defining an outer surface and extending between a first, leading end and a second, trailing end, the second end including a tool-receiving portion for receiving a tool, the elongate body including a central canal for receiving a flowable material, and having one or more channels in fluid communication with the central canal, the channels being located along one side of the elongate body, wherein the elongate body further includes a depressed, cutaway portion extending into the outer surface of the elongate body, the depressed, cutaway portion sized and shaped for containing the area where flowable material is dispersed, the one or more channels residing within the depressed, cutaway portion;

implanting the implantable device into a subchondral level of the bone, while preserving an articular surface of the bone, such that the one or more channels are directed toward the subchondral bone defect; and

injecting a flowable material into the implantable device, wherein the flowable material is dispersed in a directionally controlled manner to the subchondral bone defect for treatment of the defect.

14. The method of claim 13, wherein after implantation, the implantable device provides mechanical support to stabilize the subchondral bone defect.

15. The method of claim 13, wherein implanting the implantable device comprises releasably coupling an insertion tool to the tool-receiving portion of the elongate body.

16. The method of claim 15, wherein implanting the implantable device comprises at least one of slip-fitting and press-fitting the implantable device into the subchondral level of the bone.

17. The method of claim 15, wherein the elongate body of the implantable device is at least partially threaded, and wherein implanting the implantable device comprises rotating the implantable device in a first direction to drive the implantable device into the sucbhondral level of the bone.

18. The method of claim 13, wherein the flowable material is injected into the implantable device with an injection tool having a hollow shaft insertable into the central canal of the implantable device, the injection tool including one or more channels configured to align with one or more channels of the implantable device to allow extrusion of the flowable material out of the injection tool and through the implantable device.

19. The method of claim 13, further comprising implanting a second implantable device into the subchondral level of the bone, the second implantable device comprising an elongate body extending between a first, leading end and a second, trailing end, the second end including a tool-receiving portion for receiving a tool, the elongate body including a central canal for receiving a flowable material, and having one or more channels in fluid communication with the central canal.

20. A method of treating a bone defect, comprising:

providing or obtaining a first implantable device for insertion into bone, the first implantable device comprising an elongate body extending between a first, leading end and a second, trailing end, the second end including a tool-receiving portion for receiving a tool, the elongate body including a central canal for receiving a flowable material, and having one or more channels in fluid communication with the central canal, the channels being located along one side of the elongate body;

providing or obtaining a second implantable device for insertion into bone, the second implantable device comprising an elongate body extending between a first, leading end and a second, trailing end, the second end including a tool-receiving portion for receiving a tool, the elongate body including a central canal for receiving a flowable material, and having one or more channels in fluid communication with the central canal, the channels being located along one side of the elongate body,

wherein the elongate bodies of the first and second implantable devices each include a depressed, cutaway portion for containing the area where the flowable material can extrude, the one or more channels residing within the depressed, cutaway portion;

implanting the first and second implantable devices into a subchondral level of a bone such that the one or more channels of each device are oriented towards each other; and

injecting a flowable material into at least one of the implantable devices.