Vessels, contact surfaces, and coating and inspection apparatus and methods
First Claim
1. A catheter comprisinga substrate defining a contact surface for contact between the substrate and a fluid or tissue;
- anda lubricity layer deposited on the contact surface and configured to provide a lower sliding force or breakout force for the contact surface than for the uncoated substrate;
the lubricity layer having one of the following atomic ratios, measured by X-ray photoelectron spectroscopy (XPS), SiwOxCy or SiwNxCy, where w is 1, x in this formula is from about 0.5 to 2.4, and y is from about 0.6 to about 3;
the lubricity layer having a thickness by transmission electron microscopy (TEM) between 10 and 1000 nm;
the lubricity layer deposited by plasma enhanced chemical vapor deposition (PECVD) under conditions effective to form a coating from a precursor selected from a linear siloxane, a monocyclic siloxane, a polycyclic siloxane, a polysilsesquioxane, a linear silazane, a monocyclic silazane, a polycyclic silazane, a polysilsesquiazane, a silatrane, a silquasilatrane, a silproatrane, an azasilatrane, an azasilquasiatrane, an azasilproatrane, or a combination of any two or more of these precursors.
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Accused Products
Abstract
Methods for processing a contact surface, for example to provide a gas barrier or lubricity or to modify the wetting properties on a medical device, are disclosed. First and second PECVD or other contact surface processing stations or devices and a contact surface holder comprising a contact surface port are provided. An opening of the contact surface can be seated on the contact surface port. The interior contact surface of the seated contact surface can be processed via the contact surface port by the first and second processing stations or devices. contact surface barrier, lubricity and hydrophobic coatings and coated contact surfaces, for example syringes and medical sample collection tubes are disclosed. A contact surface processing system and contact surface inspection apparatus and methods are also disclosed.
937 Citations
9 Claims
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1. A catheter comprising
a substrate defining a contact surface for contact between the substrate and a fluid or tissue; - and
a lubricity layer deposited on the contact surface and configured to provide a lower sliding force or breakout force for the contact surface than for the uncoated substrate; the lubricity layer having one of the following atomic ratios, measured by X-ray photoelectron spectroscopy (XPS), SiwOxCy or SiwNxCy, where w is 1, x in this formula is from about 0.5 to 2.4, and y is from about 0.6 to about 3; the lubricity layer having a thickness by transmission electron microscopy (TEM) between 10 and 1000 nm; the lubricity layer deposited by plasma enhanced chemical vapor deposition (PECVD) under conditions effective to form a coating from a precursor selected from a linear siloxane, a monocyclic siloxane, a polycyclic siloxane, a polysilsesquioxane, a linear silazane, a monocyclic silazane, a polycyclic silazane, a polysilsesquiazane, a silatrane, a silquasilatrane, a silproatrane, an azasilatrane, an azasilquasiatrane, an azasilproatrane, or a combination of any two or more of these precursors. - View Dependent Claims (2, 3, 4, 5)
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6. A catheter comprising
a substrate defining a contact surface for contact between the substrate and a fluid or tissue; - and
a barrier layer deposited on the contact surface and configured to reduce the transmission of a fluid to or from the contact surface; the barrier layer having one of the following atomic ratios, measured by X-ray photoelectron spectroscopy (XPS), SiOx or SiNx, where x is from about 0.5 to 2.4; the barrier layer having a thickness by transmission electron microscopy (TEM) between 1 and 1000 nm; the barrier layer deposited by plasma enhanced chemical vapor deposition (PECVD) under conditions effective to form a coating from a precursor selected from a linear siloxane, a monocyclic siloxane, a polycyclic siloxane, a polysilsesquioxane, a linear silazane, a monocyclic silazane, a polycyclic silazane, a polysilsesquiazane, a silatrane, a silquasilatrane, a silproatrane, an azasilatrane, an azasilquasiatrane, an azasilproatrane, or a combination of any two or more of these precursors.
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7. A catheter comprising a substrate defining a contact surface for contact between the substrate and a fluid or tissue;
- the contact surface having a hydrophobic layer having the composition;
SiOxCy or SiNxCy, where x in this formula is from about 0.5 to 2.4 and y is from about 1.6 to about 3, of the type made by;providing a precursor selected from a linear siloxane, a monocyclic siloxane, a polycyclic siloxane, a polysilsesquioxane, an alkyl trimethoxysilane, a linear silazane, a monocyclic silazane, a polycyclic silazane, a polysilsesquiazane, or a combination of any two or more of these precursors; applying the precursor to a contact surface under conditions effective to form a coating; and polymerizing or crosslinking the coating, or both, to form a hydrophobic contact surface having a higher contact angle than the untreated contact surface. - View Dependent Claims (8, 9)
- the contact surface having a hydrophobic layer having the composition;
Specification