Nasal delivery
First Claim
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1. A delivery device for delivering one or more substances to a nasal cavity of a subject for systemic uptake, the delivery device comprising:
- a nosepiece for insertion into the nasal cavity of the subject, the nosepiece including an outlet unit having a first nozzle; and
a substance supply unit operable to deliver a first substance to the first nozzle;
wherein the first nozzle is configured to deliver the first substance to;
(i) either or both of a first region and/or a second region, or (ii) substantially only to the first region; and
wherein the first region is an anterior region of the nasal cavity of the subject, the anterior region being anterior to a nasal valve of the subject, and the second region is an anterior section of a posterior region of the nasal cavity of the subject, the anterior section of the posterior region being posterior of the nasal valve of the subject; and
a second nozzle configured to deliver a second substance to a third region, wherein the third region is a posterior section of the posterior region of the nasal cavity of the subject, the posterior section of the posterior region being posterior to the anterior section of the posterior region.
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Abstract
A delivery device for and method of delivering a dose of substance for systemic uptake to a nasal cavity of a subject, the delivery device comprising: a nosepiece unit for insertion into a nasal cavity of a subject and comprising an outlet unit which includes at least one nozzle for delivering substance for systemic uptake substantially only to surfaces in one or both of the anterior region and an anterior section of the posterior region of the nasal cavity of the subject; and a substance supply unit which is operable to deliver a dose of substance to the at least one nozzle.
83 Citations
18 Claims
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1. A delivery device for delivering one or more substances to a nasal cavity of a subject for systemic uptake, the delivery device comprising:
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a nosepiece for insertion into the nasal cavity of the subject, the nosepiece including an outlet unit having a first nozzle; and a substance supply unit operable to deliver a first substance to the first nozzle; wherein the first nozzle is configured to deliver the first substance to;
(i) either or both of a first region and/or a second region, or (ii) substantially only to the first region; andwherein the first region is an anterior region of the nasal cavity of the subject, the anterior region being anterior to a nasal valve of the subject, and the second region is an anterior section of a posterior region of the nasal cavity of the subject, the anterior section of the posterior region being posterior of the nasal valve of the subject; and a second nozzle configured to deliver a second substance to a third region, wherein the third region is a posterior section of the posterior region of the nasal cavity of the subject, the posterior section of the posterior region being posterior to the anterior section of the posterior region. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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Specification