Device for harvesting, processing, and transferring adipose tissue

• US 9,278,165 B2
• Filed: 05/15/2013
• Issued: 03/08/2016
• Est. Priority Date: 05/30/2012
• Status: Active Grant

• Current Assignee: Lifecell Corporation (Abbvie Incorporated)
• Original Assignee: Lifecell Corporation (Abbvie Incorporated)
• Inventors: Connor, Jerome, Barere, Aaron M., Park, Sangwook
• Primary Examiner(s): Nagpaul, Jyoti
• Application Number:
  US13/894,912
• Publication Number:
  US 20130324966A1
• Time in Patent Office: 1,028 Days
• US Class Current: 1/1
• CPC Class Codes: A61M 1/63 with means for emptying the suction container, e.g. by interrupting suction
• CPC Class Codes: A61M 1/79 Filters for solid matter specially adapted for dental use A61C17/065
• CPC Class Codes: A61M 1/892 with treatment of the collected fat
• CPC Class Codes: A61M 1/895 with means for reinjection of collected fat
• CPC Class Codes: A61M 2202/08 Lipoids
• CPC Class Codes: A61M 2205/75 with filters
• CPC Class Codes: A61M 5/00 Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests vaccination appliances for veterinary use A61D1/025 ; tube connectors, tube couplings, valves or branch units specially adapted for medical use A61M39/00; containers specially adapted for medical or pharmaceutical purposes A61J1/00; combinations of vial and syringe for mixing or transferring their contents A61J1/20; holders for containers for collecting, storing or administering blood or medical fluids A61J1/16

Abstract

The present disclosure provides devices and methods for harvesting and processing tissue from patients for grafting. The devices can include a tissue collection chamber for ascetically collecting, processing, and/or re-implanting adipose tissue.

Claims

1. A device for preparing tissue comprising:

a container;

a filter having a peripheral rim portion, wherein the filter is positioned within the container such that the peripheral rim portion engages at least one inner surface of the container and includes side walls that project downward from the peripheral rim to define a first tissue collection chamber and a second filtrate collection chamber; and

a flexible membrane, wherein the edges of the flexible membrane are connected to at least one of an inner surface of the container within the peripheral rim and the peripheral rim of the filter to form a fluid-tight seal between at least a part of the at least one inner surface of the device and the first tissue collection chamber, wherein the flexible membrane has sufficient flexibility to allow expansion of the membrane into the first tissue collection chamber to force material contained within the first tissue collection chamber through the filter and into the second filtrate collection chamber upon application of a pressure to the flexible membrane.

2. The device of claim 1, further comprising at least one port in fluid communication with a space formed between the flexible membrane and at least one inner surface of the device.

3. The device of claim 1, further comprising at least two ports, wherein at least one port has an opening within the filtrate collection chamber, and the at least one other port has an opening within the tissue collection chamber.

4. The device of claim 3, wherein at least one of the ports is bidirectional.

5. The device of claim 3, further comprising a negative pressure source.

6. The device of claim 5, wherein the negative pressure source is a vacuum.

7. The device of either of claims 5-6, wherein the negative pressure source is in fluid communication with the filtrate collection chamber.

8. The device of claim 1, further comprising a pressure measuring element.

9. The device of claim 1, wherein the filter comprises a rigid material.

10. The device of claim 9, wherein the filter comprises a material selected from medical grade plastic, biocompatible plastic, fiberglass, and medical grade metals.

11. The device of claim 10, wherein the filter comprises stainless steel.

12. The device of claim 1, wherein the filter is conical.

13. The device of claim 12, wherein the filter can hold a volume ranging from about 50 cubic centimeters to about 500 cubic centimeters.

14. The device of claim 12, wherein the filter can hold a volume ranging from about 500 cubic centimeters to about 2000 cubic centimeters.

15. The device of claim 1, wherein the filter can hold a volume ranging from about 50 cubic centimeters to about 2000 cubic centimeters.

16. The device of claim 1, wherein the flexible membrane comprises an elastomeric material.

17. The device of claim 1, wherein the flexible membrane is made from silicone.

18. The device of claim 1, further comprising a tissue suction instrument operably connected to the tissue collection chamber.

19. The device of claim 18, further comprising a tissue transfer or delivery instrument operably connected to the tissue collection chamber.

20. The device of any one of claims 18-19, wherein the device comprises a cannula.

21. The device of claim 1, further comprising a tissue washing fluid source in fluid communication with the tissue collection chamber.

22. The device of claim 21, wherein the tissue washing fluid source is selected from the group consisting of ringer'"'"'s lactate, detergent, collagenase, stem cells, and pH buffers.