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Microfluidic chip comprising several cylinder-piston arrangements

  • US 9,278,352 B2
  • Filed: 09/27/2011
  • Issued: 03/08/2016
  • Est. Priority Date: 09/30/2010
  • Status: Expired due to Fees
First Claim
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1. A microfluidic arrangement comprising:

  • a substrate in which a microfluidic structure is formed, the latter having a plurality of parallel adjacent channels each having an open top side, and at least one common supply line, into which one end of the adjacent channels open, wherein a portion of each of the adjacent channels forms a cylinder section of a cylinder/piston arrangement, with the other end of the adjacent channels forming an aperture sized to receive a piston;

    a plurality of elongate pistons each associated with one of the plurality of channels and having a cross sectional area significantly less than the associated channel, wherein the pistons each have a free end which extends through the aperture into the cylinder section of one of the channels;

    a cover cooperating with the top side of the substrate and configured to sealingly isolate the parallel adjacent channels from the outside environment;

    and a sealing arrangement, which is stationary relative to the substrate, for sealing each of the pistons in an associated cylinder adjacent a second end of the channel;

    wherein the pistons are configured to move axially through the sealing arrangement, enabling the free end to move into or out of the cylinder section; and

    wherein the sealing arrangement comprises a continuous seal element which spans the plurality of adjacent channels and seals a plurality of the pistons.

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