Cutting wire assembly with coating for use with a catheter

• US 9,282,991 B2
• Filed: 06/15/2014
• Issued: 03/15/2016
• Est. Priority Date: 10/06/2010
• Status: Active Grant

• Current Assignee: REX Medical LP
• Original Assignee: REX Medical LP
• Inventors: Schur, Israel, McGuckin, James F. Jr., Bressler, James Erich
• Primary Examiner(s): FISHBACK, ASHLEY LAUREN
• Application Number:
  US14/304,971
• Publication Number:
  US 20140296888A1
• Time in Patent Office: 639 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 17/320725 with radially expandable cutting or abrading elements A61B17/32075 takes precedence
• CPC Class Codes: A61B 17/320758 with a rotating cutting instrument, e.g. motor driven A61B17/320725, A61B17/32075 and A61B17/320783 take precedence; for removing intra-ocular material A61F9/00763; endoscopic rotatable cutting instruments A61B17/32002
• CPC Class Codes: A61B 2017/22001 Angioplasty, e.g. PCTA
• CPC Class Codes: A61B 2017/22061 for spreading elements apart
• CPC Class Codes: A61B 2017/320052 Guides for cutting instruments by marking A61B2090/395
• CPC Class Codes: A61B 2017/320733 with a flexible cutting or scraping element, e.g. with a whip-like distal filament member

Abstract

A device for treating a lesion in a body lumen to enlarge a passageway in the body lumen having at least one cutting member and a tracking member. The at least one cutting member has a cutting surface and a separate material associated therewith. The cutting member and tracking member are connected at a distal portion and insertable into the body lumen as a unit, the cutting member configured for movement in a direction transverse to a longitudinal axis of the tracking member to widen a gap between the cutting member and tracking member at least at a distal region and to apply the separate material to an interior of the lesion.

Claims

1. A device for treating a lesion in a body lumen to enlarge a passageway in the body lumen, the device comprising at least one cutting member and a tracking member, the at least one cutting member having a proximal portion, a distal portion, a cutting surface and a separate material associated therewith, the tracking member having a proximal portion and a distal portion, the at least one the cutting member and tracking member being connected at a distal portion and insertable into the body lumen as a unit, the at least one cutting member configured for movement in a direction transverse to a longitudinal axis of the tracking member to widen a gap between the at least one cutting member and tracking member at least at a distal region and to apply the separate material to an interior of the lesion, wherein the cutting surface is on a first surface opposite a second surface facing the tracking member, the cutting surface formed only in a distal region of the at least one cutting member and the separate material is only associated with the distal region of the at least one cutting member having the cutting surface.

2. The device of claim 1, wherein the tracking member includes a plurality of marker bands.

3. The device claim 1, wherein the at least one cutting member includes a plurality of cutting members, the plurality of cutting members are connected at a distal portion to the tracking member and inserted as a unit through a lumen of the catheter.

4. The device of claim 1, in combination with a catheter having a lumen and an expandable portion, wherein the cutting surface is configured to treat the lesion to enlarge the passageway in the body lumen when moved by the expandable portion of the catheter to widen the gap between the at least one cutting member and tracking member.

5. The device of any of claim 1, wherein the tracking member has a coil at a distal tip, and further comprising shrink wrap over a connection region of the tracking and at least one cutting member.

6. The device of any of claim 1, wherein the at least one cutting member is a wire and the tracking member is a wire.

7. The device of claim 1, wherein the separate material is a thrombolytic agent.

8. The device of claim 1, wherein the separate material is an anti-coagulant.

9. The device of claim 1, wherein the at least one cutting member is substantially circular in cross-section in a proximal region and substantially triangular in cross-section in a distal region.

10. The device of claim 1, wherein the separate material is a material applied to an external region of the at least one cutting member.

11. The device of claim 1, wherein the separate material is embedded in the at least one cutting member and leaches into the lesion.

12. A device for treating a lesion in a body lumen to enlarge a passageway in the body lumen, the device comprising at least one cutting member and a tracking member, the at least one cutting member having a proximal portion, a distal portion, a cutting surface and a separate material associated therewith, the tracking member having a proximal portion and distal portion, the at least one cutting member and tracking member being connected at a distal portion and insertable into the body lumen as a unit, the at least one cutting member configured for movement in a direction transverse to a longitudinal axis of the tracking member to widen a gap between the at least one cutting member and tracking member at least at a distal region and to apply the separate material to an interior of the lesion, wherein the at least one cutting member has a first portion of a first configuration and a second portion of a second configuration, the second portion including a cutting surface and the first portion being atraumatic, wherein the separate material is placed on the second portion and not on the first portion, wherein a height of the second portion is less than a height of the first portion.

13. A method of treating a lesion in a body lumen, the method comprising:

inserting a tracking member and at least one cutting member having a separate material associated therewith into the body lumen;

inserting a catheter over the tracking member so the tracking member extends through a first lumen of the catheter and the at least one cutting member does not extend through the first lumen; and

moving the at least one cutting member away from the tracking member into cutting contact with the lesion to enlarge a passageway in the body lumen and apply the separate material to an interior of the lesion, wherein the step of inserting the at least one cutting member and tracking member comprises the step of inserting the at least one cutting member and tracking member through a lumen of an angioplasty catheter, the angioplasty catheter being different than the catheter inserted over the tracking member.

14. The method of claim 13, wherein the step of inserting the at least one cutting member and tracking member comprises the step of inserting the at least one cutting member and tracking member through a lumen of the same catheter subsequently inserted over the tracking member.

15. The method of claim 13, wherein the step of moving the at least one cutting member away from the tracking member includes expanding an expandable balloon of a catheter, the step of expanding the balloon causes the at least one cutting member to be moved radially with respect to the catheter and a gap between the at least one cutting member and tracking member to widen.

16. The method of claim 13, wherein the at least one cutting member and tracking member are attached at a distal end and inserted as a unit through the lumen of the catheter.