Patient temperature control catheter with outer sleeve cooled by inner sleeve

• US 9,283,110 B2
• Filed: 09/18/2012
• Issued: 03/15/2016
• Est. Priority Date: 09/20/2011
• Status: Active Grant

• Current Assignee: Zoll Circulation Incorporated (Asahi Kasei Corporation)
• Original Assignee: Zoll Circulation Incorporated (Asahi Kasei Corporation)
• Inventors: Lim, Alex L., Gurukula, Venkata Vishnu, Dabrowiak, Jeremy T., Helkowski, Richard A.
• Primary Examiner(s): Dvorak, Linda
• Assistant Examiner(s): Ekrami, Yasamin
• Application Number:
  US13/622,104
• Publication Number:
  US 20130073014A1
• Time in Patent Office: 1,274 Days
• Field of Search: 606 21- 26, 607/105, 607/113, 607 22- 26
• US Class Current: 1/1
• CPC Class Codes: A61F 2007/0054 with a closed fluid circuit, e.g. hot water
• CPC Class Codes: A61F 2007/0056 for cooling
• CPC Class Codes: A61F 2007/0094 using a remote control
• CPC Class Codes: A61F 2007/0096 with a thermometer
• CPC Class Codes: A61F 2007/126 for invasive application, e.g. for introducing into blood vessels
• CPC Class Codes: A61F 7/0085 Devices for generating hot or cold treatment fluids
• CPC Class Codes: A61F 7/12 Devices for heating or cooling internal body cavities
• CPC Class Codes: A61M 2025/0004 having two or more concentrically arranged tubes for forming a concentric catheter system
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 25/00 Catheters; Hollow probes dilators A61M29/00; peritoneal catheters A61M1/285; tracheal tubes A61M16/04; for drainage A61M27/00; for uterus, vagina or rectum A61M31/00 ; for measuring or testing A61B; materials for catheters A61L29/00

Abstract

A catheter has an inner sleeve through which refrigerant circulates to and from a source of refrigerant. The catheter also has an outer sleeve surrounding the inner sleeve, including a distal end thereof. The outer sleeve is filled with a frozen biocompatible substance. The refrigerant is separated from the biocompatible substance by one or more walls of the inner sleeve such that the refrigerant is isolated from a patient in whom the catheter is positioned by both the inner sleeve and the frozen biocompatible substance. The refrigerant circulates through the catheter when the catheter is positioned in the patient to maintain the biocompatible substance frozen as heat is transferred from the patient to the biocompatible substance.

Claims

1. A catheter, comprising:

an inner sleeve through which refrigerant can circulate to and from a source of refrigerant;

an outer sleeve surrounding the inner sleeve including a distal end thereof and filled with a frozen biocompatible substance, the refrigerant being separated from the biocompatible substance by one or more walls of the inner sleeve such that when the catheter is disposed in a patient, the refrigerant is isolated from the patient by both the inner sleeve and the frozen biocompatible substance, the refrigerant circulable through the catheter when the catheter is positioned in the patient to maintain the biocompatible substance frozen as heat is transferred from the patient to the biocompatible substance; and

at least one refrigerant sensor positioned between the inner and outer sleeves, the refrigerant sensor communicating with a control system engaged with the catheter and responsive to detecting refrigerant between the inner and outer sleeves, generating a signal to the control system for causing the control system to activate an audible and/or visual alarm.

2. The catheter of claim 1, comprising the refrigerant, wherein the refrigerant is a fluorinated hydrocarbon.

3. The catheter of claim 1, wherein the frozen biocompatible substance is saline.

4. The catheter of claim 1, wherein the inner sleeve is cylindrical.

5. The catheter of claim 1, wherein the inner sleeve has an opening juxtaposed with a proximal end of the inner sleeve and a closed distal end opposite the proximal end such that refrigerant may enter the inner sleeve only through the proximal end and cannot pass through the distal end.

6. The catheter of claim 1, wherein the inner and outer sleeves are coaxial with each other.

7. A system, comprising:

a catheter for cooling a patient, wherein the catheter has an inner sleeve through which refrigerant from a source of refrigerant can circulate to and from the source of refrigerant;

wherein the catheter has an outer sleeve surrounding the inner sleeve including a distal end thereof and filled with a biocompatible substance;

wherein the refrigerant can circulate through the catheter to maintain the biocompatible substance below the freezing point of the biocompatible substance as heat is transferred to the biocompatible substance; and

at least one fluorinated hydrocarbon sensor positioned between the inner and outer sleeves of the catheter, the fluorinated hydrocarbon sensor configured for communicating with a control system.

8. The system of claim 7, wherein the biocompatible substance is frozen and the outer sleeve extends the length of the inner sleeve.

9. The system of claim 7, wherein the inner sleeve of the catheter has an opening juxtaposed with a proximal end of the inner sleeve and the distal end opposite the proximal end such that refrigerant may enter the inner sleeve only through the proximal end and cannot pass through the distal end.

10. The system of claim 7, further comprising at least one control system engageable with the catheter and configured for, responsive to a signal from the fluorinated hydrocarbon sensor, generating a signal to activate an audible and/or visual alarm.

11. System comprising:

at least one catheter including an inner chamber configured to receive refrigerant therein and an outer chamber surrounding the inner chamber and configured to hold a biocompatible fluid therein, such that the biocompatible fluid can exchange heat with the refrigerant; and

a control system configured for receiving a patient temperature signal and responsive to the patient temperature control signal, selectively circulating refrigerant in the inner chamber.

12. The system of claim 11, comprising a refrigerant in the inner chamber and a biocompatible fluid in the outer chamber.

13. The system of claim 11, comprising a patient temperature sensor configured to communicate with the control system.