Methylene linked quinolinyl modulators of RORγt
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Abstract
The present invention comprises compounds of Formula I.
wherein:
- R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification.
The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.
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Citations
21 Claims
- 1. A compound of Formula I wherein:
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3. A compound of claim selected from the group consisting of:
Another embodiment of the invention is a compound selected from the group consisting of;
Specification