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Neutral active soluble truncated PH20 polypeptides and uses thereof

  • US 9,284,543 B2
  • Filed: 02/21/2012
  • Issued: 03/15/2016
  • Est. Priority Date: 12/09/2008
  • Status: Active Grant
First Claim
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1. A truncated soluble PH20 hyaluronidase, wherein:

  • the truncated PH20 hyaluronidase is neutral active;

    is soluble; and

    consists of any sequence of amino acid residues within SEQ NO;

    107 that terminates at residue 469, 470 or 471 of SEQ ID NO;

    107.

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