Device to detect malignant processes in living organisms

• US 9,289,152 B2
• Filed: 03/14/2008
• Issued: 03/22/2016
• Est. Priority Date: 03/16/2007
• Status: Expired due to Fees

• Current Assignee: Advanced Bioresearch And Technology S. A.
• Original Assignee: Advanced Bioresearch And Technology S. A.
• Inventors: Shaduri, Marina
• Primary Examiner(s): Bailey, Frederick
• Assistant Examiner(s): Navas, Jr., Edemio
• Application Number:
  US12/531,465
• Publication Number:
  US 20100103252A1
• Time in Patent Office: 2,930 Days
• Field of Search: None
• US Class Current: 1/1
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/05 Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves impedance plethysmography A61B5/0295; measuring movement of the entire body or parts thereof A61B5/11; detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof A61B5/24
• CPC Class Codes: A61B 5/415 the glands, e.g. tonsils, adenoids or thymus
• CPC Class Codes: A61B 5/418 lymph vessels, ducts or nodes
• CPC Class Codes: H04N 7/18 Closed-circuit television [CCTV] systems, i.e. systems in which the video signal is not broadcast

Abstract

The invention concerns a device for non-invasive detection of malignant processes in human body. Diagnostically informative optical data are obtained by exposing human fingertips to pulsed electric fields strong enough to initiate atmospheric pressure corona discharge. The device that provides reliable information useful for detection of cancer-specific spectral signatures comprises a transparent electrode (4) to generate electric impulses, which is covered by a rigid transparent insulator (3); a flexible transparent membrane (2) positioned loosely on the free surface of the rigid insulator to facilitate the recombination processes; a dark opaque membrane (1) positioned on the transparent membrane to eliminate spurious light; an image-receiving camera (5) mounted beneath the optically transparent electrode and a computer to operate the device and process recorded data. Proper arrangement of 3 dielectric layers and the recording of images when thermodynamic equilibrium is already established, significantly improves the reproducibility of optical data.

Claims

1. A device for the gas-discharge detection of malignant processes in living organisms, which comprises:

an optically transparent electrode for generating an electric field,

a dielectric, the dielectric being disposed on the optically transparent electrode and configured for electrical insulation of an object under examination, and

a progressive-scan monochrome camera positioned below the optically transparent electrode, configured to generate continuous analog video signal to be sent to a computer for further processing;

the dielectric comprising;

a rigid, transparent electrically-insulating layer;

an elastic transparent object-imaging membrane, which is positioned on top of and contacting the electrically-insulating layer;

a dark opaque elastic membrane, disposed on and contacting the object-imaging membrane to cover the object-imaging membrane and serving to absorb spurious light reflected from the object'"'"'s surface, wherein such an arrangement of rigid and elastic dielectrics is effective for acquisition of reproducible and narrower spectrum gas-discharge imagery through filtering out a majority of diagnostically irrelevant, namely cancer-nonspecific spectral components, and preserving required spectral signals in vicinity of the object under examination;

the electrode being configured to cause ionization and discharge in air surrounding the object under examination which is positioned upon the dark opaque elastic membrane and no gas is imprisoned in the plane of the dielectric.

2. A device for the gas-discharge detection of malignant processes in living organisms, which comprises:

an optically transparent electrode for generating an electric field,

a dielectric, the dielectric being configured for electrical insulation of an object under examination, and

a digital photographic camera generating discrete single images in digital presentation to be sent to a computer for further processing;

the dielectric comprising;

a rigid, transparent electrically-insulating layer;

an elastic transparent object-imaging membrane, which is tightly positioned on top of and contacting the electrically-insulating layer;

a dark opaque elastic membrane, disposed on and contacting the object-imaging membrane to cover the object-imaging membrane ne and serving to absorb spurious light reflected from the object'"'"'s surface, wherein such an arrangement of rigid and elastic dielectrics is effective for acquisition of reproducible and narrower spectrum gas-discharge imagery through filtering out a majority of diagnostically irrelevant, namely cancer-nonspecific spectral components, and preserving required spectral signals in vicinity of the object under examination;

the electrode being configured to cause ionization and discharge in air surrounding the object under examination when the object is positioned upon the dark opaque elastic membrane and no gas is imprisoned in the plane of the dielectric.