System and/or method for glucose sensor calibration
First Claim
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1. A method comprising:
- obtaining samples of an electrical signal generated by a sensor, said samples having sample values responsive to a blood-glucose concentration in a patient;
obtaining blood glucose reference measurement values responsive to said blood-glucose concentration;
pairing at least some of the sample values with temporally associated blood glucose reference measurement values;
for at least one of said paired sample values, weighting said paired sample value based, at least in part, on a measure of statistical dispersion of said electrical signal, said measure of statistical dispersion of said electrical signal being a function of a blood glucose reference measurement value paired with said sample value;
determining one or more parameters of an estimator of said blood-glucose concentration based, at least in part, on said weighted paired sample values; and
controlling a pump to infuse a substance to said patient based, at least in part, on said determined one or more parameters of said estimator of said blood-glucose concentration.
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Abstract
The subject matter disclosed herein relates to systems, methods and/or devices for calibrating sensor data to be used in estimating a blood glucose concentration. A relationship between sensor measurements and reference readings may be used to estimate a relationship between sensor measurements and blood glucose concentration. Such sensor measurements may be weighted according to a decreasing function of uncertainty associated with sensor values.
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Citations
30 Claims
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1. A method comprising:
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obtaining samples of an electrical signal generated by a sensor, said samples having sample values responsive to a blood-glucose concentration in a patient; obtaining blood glucose reference measurement values responsive to said blood-glucose concentration; pairing at least some of the sample values with temporally associated blood glucose reference measurement values; for at least one of said paired sample values, weighting said paired sample value based, at least in part, on a measure of statistical dispersion of said electrical signal, said measure of statistical dispersion of said electrical signal being a function of a blood glucose reference measurement value paired with said sample value; determining one or more parameters of an estimator of said blood-glucose concentration based, at least in part, on said weighted paired sample values; and controlling a pump to infuse a substance to said patient based, at least in part, on said determined one or more parameters of said estimator of said blood-glucose concentration. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. An article comprising:
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a non-transitory storage medium comprising machine-readable instructions stored thereon which are executable by a computing platform to; obtain samples of an electrical signal generated by a sensor, said samples having sample values responsive to a blood-glucose concentration in a patient; obtain blood glucose reference measurement values indicative of said blood-glucose concentration; pair at least some of said sample values with temporally associated blood glucose reference measurement values; for at least one of said paired sample values, weighting said paired sample value based, at least in part, on a measure of statistical dispersion of said electrical signal, said measure of statistical dispersion of said electrical signal being a function of a blood glucose reference sample value paired with said sample value; determining one or more parameters of an estimator of said blood-glucose concentration based, at least in part, on said weighted paired sample values; and control a pump to infuse a substance to said patient based, at least in part, on said determined one or more parameters of said estimator of said blood-glucose concentration. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
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21. An apparatus comprising:
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a sensor to generate one or more sensor signals responsive to a blood glucose concentration in a body; a computing platform to; obtain samples of said one or more signals, said samples having sample values responsive to said blood-glucose concentration in a patient; obtain blood glucose reference measurement values responsive to said blood-glucose concentration; for at least one of said paired sample values, weighting said paired sample value based, at least in part, on a measure of statistical dispersion of said electrical signal, said measure of statistical dispersion of said one or more sensor signals being a function of a blood glucose reference sample value paired with said sample value; determine one or more parameters of an estimator of said blood-glucose concentration based, at least in part, on said weighted paired sample values; and control a pump to infuse a substance to said patient based, at least in part, on said determined one or more parameters of said estimator of said blood-glucose concentration. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28, 29, 30)
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Specification