Processes for preparing JAK inhibitors and related intermediate compounds
First Claim
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1. A process of preparing a composition comprising an enantiomeric excess of the (R)-enantiomer of a compound of Formula III′
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Abstract
The present invention is related to processes for preparing chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines of Formula III, and related synthetic intermediate compounds. The chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines are useful as inhibitors of the Janus Kinase family of protein tyrosine kinases (JAKs) for treatment of inflammatory diseases, myeloproliferative disorders, and other diseases.
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1 Claim
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1. A process of preparing a composition comprising an enantiomeric excess of the (R)-enantiomer of a compound of Formula III′
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