Emulsion cosmetic compositions containing resveratrol derivatives and silicone surfactant

• US 9,295,621 B2
• Filed: 05/27/2008
• Issued: 03/29/2016
• Est. Priority Date: 07/31/2007
• Status: Active Grant

• Current Assignee: ELC Management LLC (The Estee Lauder Companies Inc.)
• Original Assignee: ELC Management LLC (The Estee Lauder Companies Inc.)
• Inventors: Maes, Daniel H., Mohammadi, Fatemeh, Qu, Lisa, Czarnota, Anna, Mammone, Thomas, Declercq, Lieve, Zecchino, Julius R.
• Primary Examiner(s): Fisher, Abigail
• Assistant Examiner(s): KASSA, JESSICA M
• Application Number:
  US12/127,414
• Publication Number:
  US 20090035237A1
• Time in Patent Office: 2,863 Days
• US Class Current: 1/1
• CPC Class Codes: A61K 8/06 Emulsions
• CPC Class Codes: A61K 8/347 Phenols
• CPC Class Codes: A61K 8/892 modified by a hydroxy group, e.g. dimethiconol
• CPC Class Codes: A61Q 1/02 Preparations containing skin colorants, e.g. pigments preparations in powder form A61Q1/12
• CPC Class Codes: A61Q 1/10 for eyes, e.g. eyeliner, mascara
• CPC Class Codes: A61Q 17/04 Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin

Abstract

An emulsion cosmetic composition comprising at least one resveratrol derivative, an aqueous phase, and an oil phase, having at least one silicone surfactant, and a method for preparing emulsions capable of delivering active resveratrol to the skin.

Claims

1. An emulsion cosmetic composition comprising esters consisting of a mixture of:

3-phosphate-5,4′

-dihydroxystilbene,

4′

-phosphate-3,5′

-hydroxystilbene,

3,5-diphosophate-4′

-hydroxystilbene,

3,4′

-diphosphate-5-hydroxystilbene; and

3,5,4′

-triphosphate stilbene;

and at least one DNA repair enzyme.

2. The composition of claim 1 wherein the mixture is dispersed or solubilized in the aqueous phase of the emulsion.

3. The composition of claim 1 wherein the mixture is reacted with sodium hydroxide and the DNA repair enzyme is selected from Micrococcus lysate, Arabidopsis thaliana extract and mixtures thereof.

4. The composition of claim 1 wherein the composition is a skin cream or lotion and comprises a mixture of volatile and nonvolatile silicones, at least one ester oil, and at least one humectant.

5. The composition of claim 1 wherein the composition is a skin cream or lotion and comprises at least one volatile silicone, at least one oil phase structuring agent, at least one aqueous phase structuring agent.

6. The composition of claim 1 wherein the composition is a foundation makeup composition wherein the oil phase comprises a mixture of volatile and nonvolatile silicones, at least one humectant, and particulates.

7. The composition of claim 6 wherein the particulates comprise a mixture of pigments and powders.

8. The composition of claim 1 which is a mascara.

9. The composition of claim 1 which is a skin cream, lotion, or makeup, further comprising a chemical sunscreen.

10. The composition of claim 9 wherein the chemical sunscreen is a UVA sunscreen.

11. A method for manufacturing an emulsion cosmetic composition for delivering a phosphate esters of resveratrol to skin, said phosphate esters consisting of a mixture of:

3-phosphate-5,4′

-dihydroxystilbene;

4′

-phosphate-3,5-dihydroxystilbene;

3,5-diphosphate-4′

-hydroxystilbene;

3,4′

-diphosphate-5-hydroxystilbene; and

3,5,4′

-triphosphate stilbene;

comprising separately combining the oil phase and the water phase ingredients, solvating or dispersing the phosphate esters of resveratrol into the water phase or the oil phase, then emulsifying the phases to create a water and oil emulsion where the phosphate esters are hydrolytically stable in the emulsion but hydrolyzes to active resveratrol when the emulsion is applied to skin.

12. The method of claim 11 wherein the phosphate esters of resveratrol are neutralized with sodium hydroxide.

13. The method of claim 12 wherein the phosphate esters of resveratrol are neutralized with sodium hydroxide prior to being solvated or dispersed into the emulsion.