Method and apparatus to detect ischemia with a pressure sensor

• US 9,301,698 B2
• Filed: 10/31/2008
• Issued: 04/05/2016
• Est. Priority Date: 10/31/2008
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Audet, Sarah A., Carney, James K., Combs, William J., Bennett, Tommy D., Kjellstrom, Barbro M. L.
• Primary Examiner(s): LEVICKY, WILLIAM J
• Application Number:
  US12/263,423
• Publication Number:
  US 20100114230A1
• Time in Patent Office: 2,713 Days
• Field of Search: 600/508, 600513-518, 607/4, 607/5, 607/6, 607/9, 607/14
• US Class Current: 1/1
• CPC Class Codes: A61B 5/02055 Simultaneously evaluating both cardiovascular condition and temperature
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/4836 Diagnosis combined with treatment in closed-loop systems or methods A61B5/0036 takes precedence
• CPC Class Codes: A61B 5/686 Permanently implanted devices, e.g. pacemakers, other stimulators, biochips A61B5/6861 takes precedence
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 7/00 Instruments for auscultation
• CPC Class Codes: A61N 1/36514 controlled by a physiological quantity other than heart potential, e.g. blood pressure controlled by two or more physical parameters A61N1/36585
• CPC Class Codes: A61N 1/36564 controlled by blood pressure
• CPC Class Codes: A61N 1/37258 Alerting the patient

Abstract

The present disclosure provides an apparatus and method of detecting ischemia with a pressure sensor. The method can include obtaining a pressure signal and determining a pressure rate of change. The method can also include identifying at least one of impaired relaxation and impaired contractility in order to detect ischemia.

Claims

1. An implantable medical device comprising:

a data collection module configured to obtain a pressure signal;

a data processing module coupled to the data collection module,

the data processing module configured to determine a pressure rate of change based on the pressure signal;

the data processing module configured to identify at least one of impaired relaxation and impaired contractility based on a maximum value of the pressure rate of change in order to detect ischemia; and

a therapy module coupled to the data processing module, the therapy module configured to at least one of deliver therapy and generate an alert when the at least one of impaired relaxation and impaired contractility is identified.

2. The device of claim 1 wherein the data collection module obtains the pressure signal using a pressure sensor located in one of the left ventricle, the right ventricle, the left atrium, and the pulmonary artery.

3. The device of claim 1 wherein the data collection module obtains a baseline pressure signal.

4. The device of claim 3 wherein the data collection module obtains the pressure signal and the baseline pressure signal from a single sensor.

5. The device of claim 1 wherein the data collection module obtains at least one complementary signal from at least one complementary sensor including at least one of heart rate, heart rate variability, time of day, heart sounds, patient activity, impedance, core body temperature, respiration rate, mixed venous oxygen saturation, wall contractility, wall tension, pulse oximetry, pulse pressure, number of premature ventricular contractions, non-sustained ventricular tachycardia, and sustained ventricular tachycardia.

6. The device of claim 5 wherein the data processing module analyzes the pressure signal and the at least one complementary signal to determine if the pressure signal represents a normal hemodynamic response.

7. The device of claim 1 wherein the data collection module obtains the pressure signal from one of a heart'"'"'s right side and a heart'"'"'s left side.

8. The device according to claim 1 wherein the maximum value comprises maximum rate of pressure increase .

9. The device according to claim 1 wherein the maximum value comprises maximum rate of pressure decrease.