MR-angiography with non-cartesian signal acquisition

• US 9,304,180 B2
• Filed: 06/29/2012
• Issued: 04/05/2016
• Est. Priority Date: 06/29/2011
• Status: Active Grant

• Current Assignee: Siemens Healthineers AG (Siemens AG)
• Original Assignee: Siemens AG
• Inventors: Schmitt, Peter
• Primary Examiner(s): Peng, Bo J
• Application Number:
  US13/537,376
• Publication Number:
  US 20130006098A1
• Time in Patent Office: 1,376 Days
• Field of Search: 600/419
• US Class Current: 1/1
• CPC Class Codes: G01R 33/4824 using a non-Cartesian trajectory
• CPC Class Codes: G01R 33/5635 Angiography, e.g. contrast-enhanced angiography [CE-MRA] or time-of-flight angiography [TOF-MRA]

Abstract

In a method and apparatus for the creation of an MR image of a vascular structure of an examination region, the spins in the examination region are saturated by the irradiation of at least one RF saturation signal, which delivers a lower signal intensity as spins in a subsequent MR signal recording for the creation of the MR angiographic image, which flow through at least one blood vessel into the examination region, and are not saturated by the RF saturation pulse. Raw data space of the MR angiographic image is read out with a non-Cartesian trajectory in the MR signal acquisition for the creation of the MR angiographic image.

Claims

1. A method for generating an angiographic image of a vascular structure in an examination region of a patient, comprising:

operating a magnetic resonance data acquisition unit comprising a radio-frequency (RF) antenna and gradient coils, in which a patient is located, by radiating, at a radiation time, at least one RF saturation pulse from said RF antenna in a volume of the patient that contains a vascular structure with blood flowing therein in a primary flow direction surrounded by surrounding tissue, said at least one RF pulse saturating nuclear spins, at said radiation time, in both said blood and said surrounding tissue, and subsequently acquiring operating said gradient coils to produce gradient fields to acquire raw magnetic resonance data from said vascular structure and said surrounding tissue from respective planar layers in said volume, each planar layer having a predetermined layer thickness and being oriented perpendicularly to said primary flow direction for generation of a magnetic resonance angiography image comprising said planar layers, and configuring said at least one RF saturation pulse to cause the nuclear spins saturated thereby to produce a lower signal intensity in said angiography image than nuclear spins, that flow in blood into the volume via at least one vessel of said vascular structure, that have not been saturated by said at least one RF pulse;

operating said gradient coils to produce said gradient fields so as to enter entering said raw magnetic resonance data representing said magnetic resonance angiography image along a radial trajectory of data entry points in a k-space memory comprising a plurality of data entry points, at which said raw magnetic data are entered, organized along respective axes defined by said gradient fields, with one of said axes corresponding to said primary flow direction, and said radial trajectory being orthogonal to said one of said axes, in order to produce an undersampled raw magnetic resonance data set in said k-space memory, said radial trajectory comprising, in each of said layers, a set of spokes comprising a plurality of spokes proceeding through a center of a matrix in said k-space memory, said magnetic resonance raw data being entered along said plurality of spokes in each of said layers with the respective sets of spokes in neighboring planar layers not coinciding when said neighboring layers are superimposed with each other; and

reconstructing said magnetic resonance angiographic image from the undersampled raw magnetic resonance data set entered into said k-space memory.

2. A method as claimed in claim 1 comprising defining operating said gradient coils to produce said gradient fields so as to configure said spokes of said radial trajectory to cause a frequency of respective spokes, which define a plane in said matrix, to be unevenly distributed in said plane, thereby producing an elliptical or oval field of view perpendicular to said blood flow in the magnetic resonance angiographic image.

3. A method as claimed in claim 1 comprising, during acquisition of said raw magnetic resonance data representing said magnetic resonance angiographic image, also exposing said patient in said data acquisition unit to a pulse sequence module that suppresses a fat signal from the patient.

4. A method as claimed in claim 1 comprising operating said magnetic resonance data acquisition unit with a gradient echo sequence as said pulse sequence.

5. A method as claimed in claim 4 wherein said gradient echo sequence comprises a repetition time period between two RF excitation pulses for said gradient echo, and alternating said repetition time period between two different repetition time periods.

6. A method as claimed in claim 1 comprising reconstructing said magnetic resonance angiographic image from the raw magnetic resonance data entered into said k-space memory using an iterative reconstruction procedure in which a plurality of examination regions of the patient are respectively recorded in a temporal phase series, comprising a plurality of neighboring examination regions in said phase series, and using a reconstructed magnetic resonance angiographic image of a neighboring examination region as a starting point for said iterative reconstruction procedure.

7. A method as claimed in claim 1 comprising acquiring said raw magnetic resonance data representing said magnetic resonance angiographic image while moving said patient through said magnetic resonance data acquisition unit.

8. A method as claimed in claim 1 comprising operating said gradient coils to randomly distribute said sets of spokes in said matrix in said k-space memory.

9. A method as claimed in claim 1 comprising triggering acquisition of said magnetic resonance raw data signal by ECG monitoring.

10. A magnetic resonance apparatus for generating an angiographic image of a vascular structure in an examination region of a patient, comprising:

a magnetic resonance data acquisition unit comprising a radio-frequency (RF) antenna and gradient coils;

a control unit configured to operate said magnetic resonance data acquisition unit, in which a patient is located, by radiating, at a radiation time, at least one RF saturation pulse from said RF antenna in a volume of the patient that contains vascular structure with blood flowing therein in a flow direction surrounded by surrounding tissue, said at least one RF pulse saturating nuclear spins, at said radiation time, in both said blood and said surrounding tissue, and to subsequently operate said gradient coils to produce gradient fields to acquire raw magnetic resonance data from said vascular structure and said surrounding tissue from respective planar layers in said volume, each planar layer having a predetermined layer thickness and being oriented perpendicularly to said flow direction, for generation of a magnetic resonance angiography image comprising said planar layers, and to configure said at least one RF saturation pulse to cause the nuclear spins saturated thereby to produce a lower signal intensity in said angiography image than nuclear spins that flow in blood into the volume via at least one vessel of said vascular structure, that have not been saturated by said at least one RF pulse;

a k-space memory into which said control unit is configured to operate said gradient coils to produce said gradient fields so as to enter said raw magnetic resonance data representing said magnetic resonance angiographic image along a radial trajectory of data entry points, said k-space memory comprising respective axes defined by said gradient fields, with one of said axes corresponding to said flow direction, and said radial trajectory being orthogonal to said one of said axes, in order to produce an undersampled raw magnetic resonance data set in said k-space memory; and

a processor configured to reconstruct said magnetic resonance angiographic image from the undersampled raw magnetic resonance data set entered into said k-space memory, said radial trajectory comprising, in each of said layers, a set of spokes comprising a plurality of spokes proceeding through a center of a matrix in said k-space memory, said magnetic resonance raw data being entered along said plurality of spokes in each of said layers with the respective sets of spokes in neighboring planar layers not coinciding when said neighboring layers are superimposed with each other.