Ablation probe with deployable electrodes
First Claim
Patent Images
1. A method of delivering an electric field to a target tissue, the method comprising:
- advancing a treatment probe comprising a delivery member into a patient;
advancing a guide through the lumen of the delivery member;
deploying and advancing the guide along a guide tissue penetration path;
deploying an electrode from the guide along an electrode tissue penetration path to define a treatment volume within the target tissue; and
establishing an alternating electrical current flow extending within the treatment volume of the patient using the deployed electrode, wherein the alternating electrical current flow provides a voltage field of less than 50 V/cm within the treatment volume and selectively destroys abnormally proliferating cells while leaving normal cells substantially intact within the treatment volume.
1 Assignment
0 Petitions
Accused Products
Abstract
The present invention provides systems, devices and related methods for applying electric fields for cancerous cell destruction and tissue ablation. A method can include advancing an ablation probe into a patient; deploying a guide from the delivery member along a guide tissue penetration path, deploying an electrode from the guide along an electrode tissue penetration path, and establishing current flow within the target tissue.
128 Citations
18 Claims
-
1. A method of delivering an electric field to a target tissue, the method comprising:
-
advancing a treatment probe comprising a delivery member into a patient; advancing a guide through the lumen of the delivery member; deploying and advancing the guide along a guide tissue penetration path; deploying an electrode from the guide along an electrode tissue penetration path to define a treatment volume within the target tissue; and establishing an alternating electrical current flow extending within the treatment volume of the patient using the deployed electrode, wherein the alternating electrical current flow provides a voltage field of less than 50 V/cm within the treatment volume and selectively destroys abnormally proliferating cells while leaving normal cells substantially intact within the treatment volume. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
-
-
10. A system for preferentially destroying cancerous cells in a treatment tissue volume, the system comprising:
-
a treatment probe comprising a delivery member having a long axis, a guide housed within the lumen of the delivery member and configured to be deployed from a sidewall opening of the delivery member and an electrode configured to be deployed from the guide along an electrode tissue penetration path so as to be penetrated into tissue and define a treatment volume within the treatment tissue volume; and an energy source coupled with the electrode to establish an alternating electrical current flow that provides a voltage field of less than 50 V/cm within the treatment tissue volume and selectively destroys abnormally proliferating cells in the treatment tissue volume while leaving normal cells in the treatment tissue volume substantially intact. - View Dependent Claims (11, 12, 13, 14, 15, 16, 17, 18)
-
Specification