Devices and methods for collecting and analyzing fluid samples from the oral cavity
First Claim
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1. A method for collecting and analyzing a sample of a fluid from the oral cavity of a mammal, said method comprising:
- (a) positioning in said oral cavity a mouthpiece of a device comprising said mouthpiece, said mouthpiece comprising;
(i) a chamber defined by front and rear inner walls and a base inner wall of said mouthpiece, said base wall extending between said front and rear inner walls, said front and rear inner walls of said chamber comprising a plurality of openings;
(ii) a first manifold for containing a first portion of liquid and providing said first portion to said chamber through said openings of said front inner wall;
(iii) a second manifold for containing a second portion of liquid and providing said second portion to said chamber through said openings of said rear inner wall;
(iv) a first port for conveying said first portion of liquid to and from said first manifold;
(v) a second port for conveying said second portion of liquid to and from said second manifold;
(b) collecting a sample of a fluid comprising oral cavity air from said chamber, said collecting step comprising applying vacuum to said oral cavity to draw said oral cavity air from said oral cavity into the device; and
(c) conducting an analysis of said oral cavity air.
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Abstract
Devices for collecting a fluid sample from the oral cavity, the device including a mouthpiece that includes a chamber, the chamber including front and rear inner walls; and means for collecting the fluid sample from the oral cavity; and methods of collecting and analyzing samples of fluid from the oral cavity, including the steps of placing the device in the oral cavity, collecting the fluid sample and conducting an analysis of the fluid sample.
122 Citations
10 Claims
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1. A method for collecting and analyzing a sample of a fluid from the oral cavity of a mammal, said method comprising:
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(a) positioning in said oral cavity a mouthpiece of a device comprising said mouthpiece, said mouthpiece comprising; (i) a chamber defined by front and rear inner walls and a base inner wall of said mouthpiece, said base wall extending between said front and rear inner walls, said front and rear inner walls of said chamber comprising a plurality of openings; (ii) a first manifold for containing a first portion of liquid and providing said first portion to said chamber through said openings of said front inner wall; (iii) a second manifold for containing a second portion of liquid and providing said second portion to said chamber through said openings of said rear inner wall; (iv) a first port for conveying said first portion of liquid to and from said first manifold; (v) a second port for conveying said second portion of liquid to and from said second manifold; (b) collecting a sample of a fluid comprising oral cavity air from said chamber, said collecting step comprising applying vacuum to said oral cavity to draw said oral cavity air from said oral cavity into the device; and (c) conducting an analysis of said oral cavity air. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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Specification