Inhaler

• US 9,308,334 B2
• Filed: 09/28/2011
• Issued: 04/12/2016
• Est. Priority Date: 09/30/2010
• Status: Active Grant

• Current Assignee: Novartis Ag
• Original Assignee: Novartis Ag
• Inventors: Dudley, Steven, Palmer-Felgate, John, Reynolds, Sean, Breakwell, Iain, Jamin, Jon, Augustyn, Steve, Smetham, Grant, Kaye, Laura, McGarva, John
• Primary Examiner(s): Ho, Tan-Uyen (Jackie) T
• Assistant Examiner(s): Boecker, Joseph D
• Application Number:
  US13/876,601
• Publication Number:
  US 20130206142A1
• Time in Patent Office: 1,658 Days
• Field of Search: 128/203.12, 128/203.15, 128/203.21
• US Class Current: 1/1
• CPC Class Codes: A61M 11/005 using ultrasonics spraying or atomising liquids using ultrasonic vibrations in general B05B17/06
• CPC Class Codes: A61M 15/001 using ultrasonic means
• CPC Class Codes: A61M 15/0026 Hinged caps
• CPC Class Codes: A61M 15/0035 Piercing means
• CPC Class Codes: A61M 15/0043 Non-destructive separation of the package, e.g. peeling
• CPC Class Codes: A61M 15/0045 using multiple prepacked dosages on a same carrier, e.g. blisters
• CPC Class Codes: A61M 15/0066 with means for varying the dose size
• CPC Class Codes: A61M 15/0068 Indicating or counting the number of dispensed doses or of remaining doses
• CPC Class Codes: A61M 15/0085 using ultrasonics spraying or atomising liquids using ultrasonic vibrations in general B05B17/06
• CPC Class Codes: A61M 16/021 operated by electrical means A61M16/202 – A61M16/205 take precedence
• CPC Class Codes: A61M 16/161 with means for measuring the humidity
• CPC Class Codes: A61M 2016/0015 inhalation detectors
• CPC Class Codes: A61M 2016/0027 pressure meter
• CPC Class Codes: A61M 2016/0033 electrical
• CPC Class Codes: A61M 2202/064 Powder
• CPC Class Codes: A61M 2205/273 preventing reuse, e.g. of disposables
• CPC Class Codes: A61M 2205/276 preventing unwanted use
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/8206 : battery-operated
• CPC Class Codes: A61M 2230/50 : Temperature

Abstract

An inhaler, the inhaler including a body (104) and a cartridge (106), the cartridge comprising a dose storage portion (122) and an airway (124), the dose storage portion being suitable for containing a plurality of doses of an inhalable medicament, the airway including a mouthpiece (128) at an end thereof, the inhaler device configured and arranged such that a dose of inhalable medicament from the dose storage portion can be accessed and arranged in a delivery configuration for delivery to a user through the airway upon inhalation through the mouthpiece by the user, the inhaler characterized in that the cartridge is replaceably removable from the body.

Claims

1. An inhaler, the inhaler including a body and a cartridge, the cartridge comprising a dose storage portion and an airway, the dose storage portion comprising a plurality of blisters, each blister containing a pre-metered dose of an inhalable medicament, an actuator mechanism mechanically engaged with the dose storage portion for accessing and arranging in a delivery configuration a dose of medicament, and the airway for conveying the dose of medicament to a user, the airway including a mouthpiece at an end thereof, the inhaler device configured and arranged such that each of the plurality of blisters from the dose storage portion can be accessed and arranged in a delivery configuration for delivery to a user through the airway upon inhalation through the mouthpiece by the user, the cartridge being replaceably couplable to the body and characterised in that when the cartridge is coupled to the body a coupling area of the cartridge is arranged adjacent to the body and is inaccessible to a user, the area of the coupling contact area being less than the contactable surface area of the cartridge which remains accessible when the body and cartridge are coupled together, and wherein the body comprises a deagglomeration mechanism, and an electronic controller that actuates a piercing mechanism within the cartridge to pierce each of the plurality of blisters.

2. An inhaler as claimed in claim 1, in which the cartridge further includes a cover, the cover being movable between a protection position in which the cover substantially covers the mouthpiece and a use position in which the mouthpiece is exposed.

3. An inhaler as claimed in claim 1 wherein, the deagglomeration mechanism comprises an energy source and a transducer, the transducer being arranged to receive energy from the energy source and transfer at least some of that energy to the blister containing said pre-metered dose of inhalable medicament.

4. An inhaler as claimed in claim 3, in which the energy source is a source of electrical energy and the transducer includes a vibrating element.

5. An inhaler as claimed in claim 4, in which the vibrating element comprises a piezoelectric element.

6. An inhaler as claimed in claim 1, in which the cartridge includes a dose display area and the body includes a window through which at least a portion of the display area is visible when the cartridge is attached to the body.

7. An inhaler as claimed in claim 1, in which a cover is coupled to the actuator such that movement of the cover actuates the actuator, the cover being movable between a protection position in which the cover substantially covers the mouthpiece and a use position in which the mouthpiece is exposed.

8. An inhaler as claimed in claim 1, in which arranging the blister in the delivery configuration comprises movement of the blister from the storage portion to a position outside the storage portion.

9. An inhaler as claimed in claim 1, in which the cartridge also includes a drive mechanism which is coupled to an actuator such that the drive mechanism is driven by movement of the actuator between first and second positions, the drive mechanism being operable to move a blister from the dose storage portion to an opening location as the actuator is moved from the first position to the second position, the drive mechanism being further operable to move the blister back into the dose storage portion as the actuator is moved from the second position to the first position, the drive mechanism further comprising indexing to retrieve a different blister the next time the actuator is moved if the blister has been opened.