Active catheter device and associated system and method

• US 9,308,350 B2
• Filed: 03/28/2012
• Issued: 04/12/2016
• Est. Priority Date: 03/28/2011
• Status: Active Grant

• Current Assignee: North Carolina State University (University of North Carolina System)
• Original Assignee: North Carolina State University (University of North Carolina System)
• Inventors: Buckner, Gregory Dale, Veeramani, Arun Shankar, Owen, Stephen B., Jernigan, Shaphan R.
• Primary Examiner(s): Jackson, Gary
• Assistant Examiner(s): Luan, Scott T
• Application Number:
  US14/004,381
• Publication Number:
  US 20140155822A1
• Time in Patent Office: 1,476 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2017/00867 shape memory effect for prostheses A61F2210/0014
• CPC Class Codes: A61B 2018/00011 with fluids
• CPC Class Codes: A61B 2090/065 for measuring contact or contact pressure
• CPC Class Codes: A61M 2205/0266 Shape memory materials
• CPC Class Codes: A61M 25/0105 Steering means as part of the catheter or advancing means; Markers for positioning systems for detection of markers A61B
• CPC Class Codes: A61M 25/0147 with movable mechanical means, e.g. pull wires
• CPC Class Codes: A61M 25/0158 with magnetic or electrical means, e.g. by using piezo materials, electroactive polymers, magnetic materials or by heating of shape memory materials

Abstract

An active catheter device is provided. At least one elongate catheter segment includes an elongate flexible tube member defining an axis, and a pair of ferrule members operably engaged with and spaced apart along the tube member. The ferrule members are not rotatable about the axis relative to each other. At least one articulation member is operably engaged with and extends at least between the ferrule members along the tube member. Each articulation member is configured to be actuatable to cause a change in a distance between the ferrule members so as to articulate the tube member. Associated systems and methods are also provided.

Claims

1. An active catheter device, comprising:

at least one elongate catheter segment, including;

an elongate flexible tube member defining an axis;

a pair of ferrule members operably engaged with the tube member, in spaced apart relation with respect to each other, such that the ferrule members are not rotatable about the axis relative to each other;

at least one articulation member operably engaged with and extending at least between the ferrule members along the tube member, the at least one articulation member being configured to be actuatable to cause a change in a distance between the ferrule members so as to articulate the tube member, wherein the at least one articulation member is comprised of a superelastic material and is formed into a first actuated configuration, before being plastically deformed into a second configuration for operable engagement between the ferrule members, the superelastic material being configured to undergo a material phase change upon application of a stimulus thereto such that the at least one articulation member changes from the second configuration to the first configuration in response to the stimulus and thereby causes the distance between the ferrule members to change and the tube member to substantially conform thereto; and

a tensioning system configured to interact with opposed articulation members, one of the tensioning system and the opposed articulation members being operably engaged with the ferrule members, wherein actuation of one of the opposed articulation members with substantially simultaneous deactuation of the other of the opposed articulation members causes a displacement differential in the tensioning system to articulate the tube member, wherein the tensioning system comprises a lever member having a medial pivot, one end of the lever member on one side of the medial pivot being configured to engage a first displacement member operably engaged with the tube member and the other end of the lever member on the other side of the medial pivot being configured to engage a second displacement member operably engaged with the tube member opposing the first displacement member.

2. A device according to claim 1 wherein the superelastic material comprises a nickel-titanium alloy.

3. A device according to claim 1 wherein the at least one articulation member includes opposed ends and comprises an anchor member integrally formed therewith about each of the opposed ends, each anchor member being configured to operably engage one of the ferrule members.

4. A device according to claim 3 wherein the at least one articulation member and the anchor members comprise an integral nanofabricated element.

5. A device according to claim 1 further comprising an actuator element operably engaged with the at least one articulation member, the actuator element being comprised of a superelastic material and being formed into a first actuated configuration, before being plastically deformed into a second configuration for operable engagement with the at least one articulation member, the superelastic material being configured to undergo a material phase change upon application of a stimulus thereto such that the actuator changes from the second configuration to the first configuration in response to the stimulus and thereby causes a force to be exerted on the at least one articulation member so as to, in turn cause the distance between the ferrule members to change.

6. A device according to claim 1 further comprising at least one sensor disposed proximate to a leading end of the elongate flexible tube member, the at least one sensor being configured to determine a force applied about the leading end along the axis and to generate a signal corresponding thereto.

7. A device according to claim 1 wherein one of the opposed articulation members is configured to slidably engage a first slot defined by the lever member between the medial pivot and the engagement with the first displacement member, and the other of the opposed articulation members is engaged with a second slot defined by the lever member between the medial pivot and the engagement with the second displacement member, and wherein changing of one of the opposed articulation members from the second configuration to the first configuration causes the opposed articulation members to laterally translate within the respective slots toward the changed one of the opposed articulation members and to correspondingly rotate the lever member about the medial pivot, the rotated lever member correspondingly increasing an effective length of one of the displacement members and decreasing an effective length of the other of the displacement members to articulate the tube member.

8. A device according to claim 1, further comprising a plurality of ferrule members operably engaged with the tube member, in successive spaced apart relation with respect thereto, such that the ferrule members are not rotatable about the axis relative to each other, wherein the at least one articulation member is operably engaged with and extends between a non-adjacent pair of the ferrule members along the tube member.

9. A device according to claim 1 further comprising a stimulus-applying element operably engaged with each of the at least one articulation member for applying the stimulus thereto.

10. A device according to claim 9 wherein the stimulus-applying element is further configured to be capable of applying heat to each of the at least one articulation member, the heat being configured to cause the material phase change in the superelastic material.

11. A device according to claim 1 further comprising a controller device operably engaged with the at least one articulation member and configured to apply the stimulus thereto.

12. An active catheter device, comprising:

at least one elongate catheter segment, including;

an elongate flexible tube member defining an axis;

a pair of ferrule members operably engaged with the tube member, in spaced apart relation with respect to each other, such that the ferrule members are not rotatable about the axis relative to each other;

at least one articulation member operably engaged with and extending at least between the ferrule members along the tube member, the at least one articulation member being configured to be actuatable to cause a change in a distance between the ferrule members so as to articulate the tube member, wherein the at least one articulation member is comprised of a superelastic material and is formed into a first actuated configuration, before being plastically deformed into a second configuration for operable engagement between the ferrule members, the superelastic material being configured to undergo a material phase change upon application of a stimulus thereto such that the at least one articulation member changes from the second configuration to the first configuration in response to the stimulus and thereby causes the distance between the ferrule members to change and the tube member to substantially conform thereto; and

a pulley assembly operably engaged with the at least one articulating member, the pulley assembly being configured to increase a force applied by the at least one articulating member, upon changing of the at least one articulation member from the second configuration to the first configuration.