Process for making hydroxylated cyclopentylpyrimidine compounds
First Claim
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1. A process, comprising, contacting a compound of formula IV, or a salt thereof:
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Abstract
The invention provides new processes for making and purifying hydroxylated cyclopenta[d]pyrimidine compounds, which are useful for the treatment of diseases such as cancer as AKT protein kinase inhibitors, including the compound (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one.
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16 Claims
- 1. A process, comprising, contacting a compound of formula IV, or a salt thereof:
Specification