Feedback systems and methods for renal denervation utilizing balloon catheter

• US 9,314,300 B2
• Filed: 09/29/2015
• Issued: 04/19/2016
• Est. Priority Date: 03/15/2013
• Status: Active Grant

• Current Assignee: St. Jude Medical Cardiology Division Incorporated (Abbott Laboratories)
• Original Assignee: St. Jude Medical Cardiology Division Incorporated (Abbott Laboratories)
• Inventors: Nabutovsky, Yelena, Karst, Edward, Qu, Fujian
• Primary Examiner(s): Holmes, Rex R
• Application Number:
  US14/868,455
• Publication Number:
  US 20160015452A1
• Time in Patent Office: 203 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 2018/0022 Balloons
• CPC Class Codes: A61B 2018/00267 having a basket shaped structure
• CPC Class Codes: A61B 2018/00285 Balloons
• CPC Class Codes: A61B 2018/00404 Blood vessels other than those in or around the heart
• CPC Class Codes: A61B 2018/00434 Neural system
• CPC Class Codes: A61B 2018/00505 Urinary tract
• CPC Class Codes: A61B 2018/00511 Kidney
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00642 with feedback, i.e. closed loop control
• CPC Class Codes: A61B 2018/00744 Fluid flow
• CPC Class Codes: A61B 2018/00761 Duration
• CPC Class Codes: A61B 2018/00773 Sensed parameters
• CPC Class Codes: A61B 2018/00863 Fluid flow
• CPC Class Codes: A61B 2090/064 for measuring force, pressure or mechanical tension
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/6853 with a balloon

Abstract

A renal denervation system includes an ablation catheter and an inflation balloon. The renal denervation catheter is insertable into a renal artery to perform a renal denervation procedure. The inflation balloon is inflatable within the renal artery, wherein one of a blood pressure condition in the renal artery resulting from operation of the inflation balloon and a performance characteristic of the inflation balloon indicates efficacy of the renal denervation procedure.

Claims

1. A renal denervation system, comprising:

an ablation catheter insertable into a renal artery to perform a renal denervation procedure including ablating a renal artery;

an inflation balloon inflatable within the renal artery, wherein one of a decay of a blood pressure condition in the renal artery resulting from operation of the inflation balloon and a performance characteristic of the inflation balloon indicates efficacy of the renal denervation procedure, wherein the decay of the blood pressure condition is measured before and after ablating the renal artery to detect a change in the decay of the blood pressure condition.

2. The renal denervation system of claim 1, wherein the inflated balloon blocks blood flow through the renal artery temporarily, and the decay of the blood pressure condition is assessed distal of the inflation balloon using a blood pressure sensor.

3. The renal denervation system of claim 1, wherein the performance characteristic of the inflation balloon includes a time period required to inflate the inflation balloon.

4. The renal denervation system of claim 3, wherein the time period required to inflate the inflation balloon to reach a pressure threshold relates to a degree of vasodilation in the renal artery.

5. The renal denervation system of claim 1, wherein the renal denervation catheter and the inflation balloon are separately insertable into the renal artery.

6. An inflation balloon configured to be inflated within a renal artery as part of a renal denervation procedure including ablating the renal artery, wherein one of a decay of a blood pressure condition in the renal artery resulting from operation of the inflation balloon and a performance characteristic of the inflation balloon indicates efficacy of the renal denervation procedure, and wherein the decay of the blood pressure condition is measured before and after ablating the renal artery to detect a change in the decay of the blood pressure condition.

7. The inflation balloon of claim 6, wherein, when inflated, the inflation balloon is configured to block blood flow through the renal artery temporarily, and the decay of the blood pressure condition is assessed distal of the inflation balloon using a blood pressure sensor.

8. The inflation balloon of claim 6, wherein the performance characteristic of the inflation balloon includes a time period required to inflate the inflation balloon.

9. The inflation balloon of claim 8, wherein the time period required to inflate the inflation balloon to reach a pressure threshold relates to a degree of vasodilation in the renal artery.

10. The inflation balloon of claim 6, wherein the inflation balloon is configured to be insertable into the renal artery separate from a renal denervation catheter.