Home-use applicators for non-invasively removing heat from subcutaneous lipid-rich cells via phase change coolants, and associates devices, systems and methods
First Claim
1. A cooling device for cooling subcutaneous lipid-rich cells in a human, comprising:
- an applicator releasably positionable in thermal communication with human skin;
an agitator;
a coolant vessel having a coolant with a first liquid/solid phase transition temperature less than about −
3°
C. and greater than about −
20°
C., wherein a solid portion of the coolant is capable of transitioning from a solid phase to a liquid/gel phase and the agitator is capable of actuating to agitate the coolant in the liquid/gel phase in the vessel to provide a generally constant temperature environment within the coolant vessel for a treatment period;
a heat transfer conduit operatively coupled to the applicator and housing a heat transfer fluid having a second liquid/solid phase transition temperature less than the first, the heat transfer fluid being isolated from fluid contact with the coolant;
a heat exchanger positioned within the coolant vessel and operatively coupled to the heat transfer conduit to transfer heat between the heat transfer fluid and the coolant, the heat exchanger including a heat exchanger conduit that, together with the heat transfer conduit and the applicator, form a sealed, closed-loop path for the heat transfer fluid; and
a fluid driver operatively coupled to the heat transfer conduit to direct the heat transfer fluid between the applicator and the heat exchanger;
a controller in communication with the fluid driver and including a computer readable medium containing instructions that, when executed, cause the fluid driver to circulate the heat transfer fluid along the closed-loop path while the constant temperature environment within the coolant vessel is at or below 0°
C. for the treatment period such thata surface of the applicator is at a temperature sufficiently low to disrupt the subcutaneous lipid-rich cells via thermal communication between the applicator and human skin, andthe surface of the applicator is at the temperature for a sufficient length of time to reduce the subcutaneous lipid-rich cells via the thermal communication between the applicator and the human skin.
1 Assignment
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Accused Products
Abstract
Home-use applicators for non-invasively removing heat from subcutaneous, lipid-rich cells via phase change coolants, and associated devices, systems and methods. A device in accordance with a particular embodiment includes an applicator releasably positionable in thermal communication with human skin, and a coolant vessel having a coolant. The device further includes a heat transfer conduit operatively coupled to the applicator and housing a heat transfer fluid that is isolated from fluid contact with the coolant. A heat exchanger is operatively coupled between the coolant vessel and the heat transfer conduit to transfer heat between the heat transfer fluid and the coolant, and a fluid driver is operatively coupled to the heat transfer conduit to direct the heat transfer fluid between the applicator and the heat exchanger.
672 Citations
20 Claims
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1. A cooling device for cooling subcutaneous lipid-rich cells in a human, comprising:
-
an applicator releasably positionable in thermal communication with human skin; an agitator; a coolant vessel having a coolant with a first liquid/solid phase transition temperature less than about −
3°
C. and greater than about −
20°
C., wherein a solid portion of the coolant is capable of transitioning from a solid phase to a liquid/gel phase and the agitator is capable of actuating to agitate the coolant in the liquid/gel phase in the vessel to provide a generally constant temperature environment within the coolant vessel for a treatment period;a heat transfer conduit operatively coupled to the applicator and housing a heat transfer fluid having a second liquid/solid phase transition temperature less than the first, the heat transfer fluid being isolated from fluid contact with the coolant; a heat exchanger positioned within the coolant vessel and operatively coupled to the heat transfer conduit to transfer heat between the heat transfer fluid and the coolant, the heat exchanger including a heat exchanger conduit that, together with the heat transfer conduit and the applicator, form a sealed, closed-loop path for the heat transfer fluid; and a fluid driver operatively coupled to the heat transfer conduit to direct the heat transfer fluid between the applicator and the heat exchanger; a controller in communication with the fluid driver and including a computer readable medium containing instructions that, when executed, cause the fluid driver to circulate the heat transfer fluid along the closed-loop path while the constant temperature environment within the coolant vessel is at or below 0°
C. for the treatment period such thata surface of the applicator is at a temperature sufficiently low to disrupt the subcutaneous lipid-rich cells via thermal communication between the applicator and human skin, and the surface of the applicator is at the temperature for a sufficient length of time to reduce the subcutaneous lipid-rich cells via the thermal communication between the applicator and the human skin. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A cooling device for cooling subcutaneous lipid-rich cells in a human, comprising:
-
a coolant vessel having a coolant with a first liquid/solid phase transition temperature less than about −
3°
C.;a heat exchanger positioned within the coolant vessel and housing a heat transfer fluid having a second liquid/solid phase transition temperature less than the first liquid/solid phase transition temperature; and an applicator operatively coupled to the heat exchanger via a closed-loop path that circulates the heat transfer fluid to transfer heat from the applicator to the coolant, wherein the first liquid/solid phase transition temperature is selected to produce a temperature at the applicator that selectively reduces the lipid-rich cells via thermal communication between the applicator and human skin, and wherein the temperature produced at the applicator is less than about 0°
C.;a fluid driver configured to be activated to direct the heat transfer fluid between the applicator and the heat exchanger; and a controller programmed to cause the fluid driver to circulate the heat transfer fluid along the closed-loop path while the coolant is capable of undergoing a solid to liquid/gel phase change such that the temperature of the applicator is sufficiently low for a sufficient length of time so as to reduce the lipid-rich cells via the thermal communication between the applicator and the lipid-rich cells, and wherein the controller is programmed to automatically deactivate the fluid driver based on a temperature of the coolant exceeding a threshold temperature. - View Dependent Claims (15, 16, 17)
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18. A cooling device for cooling subcutaneous lipid-rich cells in a human, comprising:
- a coolant vessel having a coolant with a first liquid/solid phase transition temperature less than about −
3 degrees Celsius;
a heat exchanger positioned within the coolant vessel and housing a heat transfer fluid having a second liquid/solid phase transition temperature that is less than the first liquid/solid phase transition temperature;
an applicator operatively coupled to the heat exchanger via a closed-loop path that circulates the heat transfer fluid to transfer heat from the applicator to the coolant;
a heater in thermal communication with the heat transfer fluid;
a fluid driver configured to direct the heat transfer fluid between the applicator and the heat exchanger; and
a controller programmed to automatically cause the heater to increase a temperature of the heat transfer fluid when the temperature of the heat transfer fluid is lower than a predetermined temperature, wherein the controller is programmed to automatically control activation of the fluid driver based on a temperature of the coolant, and wherein the controller is programmed to command the fluid driver to cause the heat transfer fluid to flow along the closed-loop path such that a surface of the applicator is at a sufficiently low temperature for a sufficient length of time to reduce the lipid-rich cells via thermal communication between the surface of the applicator and human skin. - View Dependent Claims (19, 20)
- a coolant vessel having a coolant with a first liquid/solid phase transition temperature less than about −
Specification