Pulse-by-pulse compliance voltage generation for an implantable stimulator

• US 9,314,632 B2
• Filed: 04/11/2013
• Issued: 04/19/2016
• Est. Priority Date: 05/17/2012
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Marnfeldt, Goran, Shi, Jess
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): Piateski, Erin M
• Application Number:
  US13/861,079
• Publication Number:
  US 20130310897A1
• Time in Patent Office: 1,104 Days
• Field of Search: 607/74
• US Class Current: 1/1
• CPC Class Codes: A61N 1/025 Digital circuitry features of electrotherapy devices, e.g. memory, clocks, processors
• CPC Class Codes: A61N 1/3605 Implantable neurostimulators for stimulating central or peripheral nerve system
• CPC Class Codes: A61N 1/36146 specified by the stimulation parameters
• CPC Class Codes: A61N 1/36153 Voltage A61N1/3616 takes precedence
• CPC Class Codes: A61N 1/37 Monitoring; Protecting
• CPC Class Codes: A61N 1/378 Electrical supply
• CPC Class Codes: H03L 1/00 Stabilisation of generator output against variations of physical values, e.g. power supply

Abstract

Circuitry for generating a compliance voltage (V+) for the current sources and/or sinks in an implantable stimulator device in disclosed. The circuitry assesses whether V+ is optimal for a given pulse, and if not, adjusts V+ for the next pulse. The circuitry uses amplifiers to measure the voltage drop across active PDACs (current sources) and NDAC (current sinks) at an appropriate time during the pulse. The measured voltages are assessed to determine whether they are high or low relative to optimal values. If low, a V+ regulator is controlled to increase V+ for the next pulse; if not, the V+ regulator is controlled to decrease V+ for the next pulse. Through this approach, gradual changes that may be occurring in the implant environment can be accounted for, with V+ adjusted on a pulse-by-pulse basis to keep the voltage drops at or near optimal levels for efficient DAC operation.

Claims

1. Circuitry configured to adjust a compliance voltage in an implantable stimulator device, comprising:

a source circuit coupled to a compliance voltage, wherein the source circuit is configured to provide a first current pulse to at least a first electrode;

a sink circuit coupled to a reference voltage, wherein the sink circuit is configured to sink the first current pulse from at least a second electrode;

a first amplifier configured to measure a first analog voltage across the source circuit;

a second amplifier configured to measure a second analog voltage across the sink circuit;

a first reference voltage generator configured to produce an optimal first analog voltage;

a second reference voltage generator configured to produce an optimal second analog voltage;

a first comparator configured to compare the measured first analog voltage to the optimal first analog voltage and to produce a first digital signal indicating whether the measured first analog voltage is high or low relative to the optimal first analog voltage;

a second comparator configured to compare the measured second analog voltage to the optimal second analog voltage and to produce a second digital signal indicating whether the measured second analog voltage is high or low relative to the optimal second analog voltage;

logic circuitry configured to assess the first and second digital signals, and configured to issue a control signal; and

regulator circuitry configured to adjust the compliance voltage in accordance with the control signal.

2. The circuitry of claim 1, wherein the first and second comparators compare the first and second analog voltages to the optimal first and second analog voltages near an end of the first current pulse.

3. The circuitry of claim 1, wherein the logic circuitry comprises an OR gate.

4. The circuitry of claim 1, wherein the regulator circuitry comprises a boost converter.

5. The circuitry of claim 1, wherein the control signal is digital.

6. The circuitry of claim 5, wherein the digital control signal enables the regulator circuitry when either the first or second digital signal indicates that the measured first or second analog voltage is low compared to the first or second optimal analog voltage.

7. The circuitry of claim 1, wherein the regulator circuitry comprises counter circuitry, and wherein the control signal increments or decrements a count of the counter circuitry.

8. The circuitry of claim 7, wherein a voltage indicative of the count is compared to a voltage indicative of the compliance voltage in the regulator circuitry.

9. The circuitry of claim 1, wherein the regulator circuitry is configured to adjust the compliance voltage for a next current pulse in accordance with the control signal.

10. The circuitry of claim 9, wherein the first current pulse comprises a therapeutic pulse and the next pulse comprises a recovery pulse.

11. The circuitry of claim 9, wherein both the first current pulse and the next pulse comprise therapeutic pulses.

23. The circuitry of claim 1, wherein the optimal first analog voltage and the optimal second analog voltage are different.

24. The circuitry of claim 1, wherein the first and second reference voltage generators comprise bandgap reference voltage generators.

12. Circuitry configured to adjust a compliance voltage in an implantable stimulator device, comprising:

a source circuit coupled to a compliance voltage, wherein the source circuit is configured to provide a first current pulse to at least a first electrode;

a sink circuit coupled to a reference voltage, wherein the sink circuit is configured to sink the first current pulse from at least a second electrode;

a first amplifier configured to measure a first voltage across the source circuit;

a second amplifier configured to measure a second voltage across the sink circuit;

a first reference voltage generator configured to produce an optimal first voltage;

a second reference voltage generator configured to produce an optimal second voltage;

a first comparator configured to compare the measured first voltage to the optimal first voltage and to produce a first digital signal indicating whether the measured first voltage is high or low relative to the optimal first voltage;

a second comparator configured to compare the measured second voltage to the optimal second voltage and to produce a second digital signal indicating whether the measured second voltage is high or low relative to the optimal second voltage;

logic circuitry configured to simultaneously assess the first and second digital signals, and configured to issue a control signal in accordance with the assessment; and

regulator circuitry configured to adjust the compliance voltage in accordance with the control signal.

13. The circuitry of claim 12, wherein the first and second comparators compare the first and second voltages to the optimal first and second voltages near an end of the first current pulse.

14. The circuitry of claim 12, wherein the logic circuitry comprises an OR gate.

15. The circuitry of claim 12, wherein the regulator circuitry comprises a boost converter.

16. The circuitry of claim 12, wherein the control signal is digital.

17. The circuitry of claim 16, wherein the digital control signal enables the regulator circuitry when either the first or second digital signal indicates that the measured first or second voltage is low compared to the first or second optimal voltage.

18. The circuitry of claim 12, wherein the regulator circuitry comprises counter circuitry, and wherein the control signal increments or decrements a count of the counter circuitry.

19. The circuitry of claim 18, wherein a voltage indicative of the count is compared to a voltage indicative of the compliance voltage in the regulator circuitry.

20. The circuitry of claim 12, wherein the regulator circuitry is configured to adjust the compliance voltage for a next current pulse in accordance with the control signal.

21. The circuitry of claim 20, wherein the first current pulse comprises a therapeutic pulse and the next pulse comprises a recovery pulse.

22. The circuitry of claim 20, wherein both the first current pulse and the next pulse comprise therapeutic pulses.

25. The circuitry of claim 12, wherein the optimal first voltage and the optimal second voltage are different.

26. The circuitry of claim 12, wherein the first and second reference voltage generators comprise bandgap reference voltage generators.