Magnetic resonance method and apparatus using dual echoes for data acquisition

• US 9,316,712 B2
• Filed: 04/17/2009
• Issued: 04/19/2016
• Est. Priority Date: 04/17/2009
• Status: Active Grant

• Current Assignee: Siemens AG, UK Research and Innovation
• Original Assignee: Medical Research Council (Government of United Kingdom), Siemens AG
• Inventors: Porter, David Andrew, Schwarzbauer, Christian
• Primary Examiner(s): Moher, Amanda Lauritzen
• Assistant Examiner(s): Akar, Serkan
• Application Number:
  US12/425,563
• Publication Number:
  US 20100268061A1
• Time in Patent Office: 2,559 Days
• Field of Search: 324/306, 324/307, 324/309, 324/312, 600/345, 600/410, 600/411
• US Class Current: 1/1
• CPC Class Codes: A61B 2018/00446 Brain
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: G01R 33/4806 Functional imaging of brain activation
• CPC Class Codes: G01R 33/5618 using both RF and gradient refocusing, e.g. GRASE
• CPC Class Codes: G01R 33/56563 caused by a distortion of the main magnetic field B0, e.g. temporal variation of the magnitude or spatial inhomogeneity of B0 G01R33/56509, G01R33/56518, G01R33/56536 take precedence

Abstract

In a method and system for acquiring magnetic resonance image data from a subject, using a data acquisition unit in which a basic magnetic field is generated, a division is designated in a planar section through the subject that divides the planar section into a first section and a second section, with the homogeneity of the basic magnetic field being better in said first section than in said second section. An echo planar imaging sequence is implemented to acquire the magnetic resonance imaging data, with magnetic resonance data being acquired from the first section only from gradient echo signals in the echo planar imaging sequence, and magnetic resonance data from said the second section being acquired from both gradient echo signals and spin echo signals in the echo planar imaging sequence. The method and apparatus are particularly suited for acquiring functional magnetic resonance imaging (fMRI) data from the brain of a subject, in which the first section is an upper portion of the brain and the second section is a lower portion of the brain.

Claims

1. A method for acquiring magnetic resonance image data, comprising the steps of:

providing a magnetic resonance scanner operated by a control computer and having a magnet system that generates a basic magnetic field;

using said control computer, making a designation of a division to place a dividing line in a planar section through a human or animal subject, dependent on anatomy represented in said planar section, that selectively divides said planar section into, and establishes in said planar section, a division comprising a first selected section on one side of said dividing line in which said basic magnetic field has a first homogeneity and a second selected section, on an opposite side of said dividing line and separated from said first selected section by said dividing line, in which said basic magnetic field has a second homogeneity that is less homogenous than said first homogeneity;

after making said division, using said control computer to generate a control protocol incorporating the designation of said division, that operates said magnetic resonance scanner to acquire magnetic resonance image data from the subject using an echo planar imaging sequence in which, according to said designation of said division, magnetic resonance image data are acquired from said first selected section only from gradient echo signals in said echo planar imaging sequence and magnetic resonance image data are acquired from said second selected section from both gradient echo signals and spin echo signals in said echo planar imaging sequence;

operating said magnetic resonance scanner from said control computer according to said control protocol to acquire said magnetic resonance image data from the subject; and

making the magnetic resonance image data from the subject available as an output from the control computer in a form allowing reconstruction of a visible image of the subject therefrom.

2. A method as claimed in claim 1 comprising using an image computer to reconstruct said visible image of the subject from said magnetic resonance image data that are output from the control computer.

3. A method as claimed in claim 1 comprising designating said division in said planar section by placing said dividing line at a location of a predetermined homogeneity threshold in said planar section.

4. A method as claimed in claim 1 comprising acquiring said magnetic resonance data from the brain of the subject, and designating said division in a sagittal section, as said planar section, through the brain of the subject.

5. A method as claimed in claim 4 comprising designating said division to divide the brain of the subject in said sagittal section into an upper region, closer to a top of the head of the subject, as said first selected section, and a lower region, farther from the top of the head of the subject, as said second selected section.

6. A method as claimed in claim 5 comprising designating said division with said upper region encompassing two-thirds of the brain of the subject in said sagittal section and with said lower section encompassing approximately one-third of the brain of the subject in said sagittal section.

7. A method as claimed in claim 1 comprising operating said magnetic resonance scanner according to said control protocol to acquire said magnetic resonance data from successive slices of the subject.

8. A method as claimed in claim 7 comprising generating an echo planar imaging sequence in said control protocol that comprises a 90°

focusing pulse, followed by a gradient echo readout gradient in which said gradient echo signal is read out, followed by a 180°

refocusing pulse, followed by a spin echo readout gradient in which said spin echo signal is read out, and comprising operating said magnetic resonance scanner according to said control protocol to execute a gradient echo loop comprising said 90°

focusing pulse and said gradient echo readout gradient to acquire said magnetic resonance data from successive slices in said first selected section and to execute a dual echo loop, comprising said 90°

focusing pulse, said gradient echo readout gradient, said 180°

refocusing pulse, and said spin echo readout gradient, to acquire said magnetic resonance data from successive slices in said second selected section.

9. A method as claimed in claim 1 comprising designating said division manually by displaying said planar section and manually placing said dividing line in the displayed planar section via an interface of said control computer.

10. A method as claimed in claim 1 comprising designating said division non-manually, automatically in said control computer by placing said dividing line in said planar section based on a magnetic field map in said planar section of said subject.

11. A method as claimed in claim 1 comprising generating said control protocol as an fMRI protocol and operating said magnetic resonance scanner to acquire said magnetic resonance image data as fMRI data.

12. A method as claimed in claim 1 comprising operating said magnetic resonance scanner to acquire said magnetic resonance data from a plurality of slices of said human or animal subject using said echo planar imaging sequence, by acquiring said magnetic resonance data from said first selected section in a plurality of slices in said first section, and acquiring said magnetic resonance imaging data from said second selected section in a plurality of other slices in said second section.

13. A method as claimed in claim 1 comprising operating said magnetic resonance scanner to acquire said magnetic resonance data from a plurality of slices of said human or animal subject using said echo planar imaging sequence, and acquiring said magnetic resonance data from said first selected section in a plurality of slices in said first section, and acquiring said magnetic resonance imaging data from said second section in a plurality of other slices in said second selected section.

14. A system for acquiring magnetic resonance image data, comprising:

a magnetic resonance scanner having a magnet system that generates a basic magnetic field;

a control computer configured to place a dividing line in a planar section through a human or animal subject, dependent on anatomy represented in said planar section, that selectively divides said planar section into, and establishes in said planar section, a division comprising a first selected section on one side of said dividing line in which said basic magnetic field has a first homogeneity and a second selected section, on an opposite side of said dividing line and separated from said first selected section by said dividing line, in which said basic magnetic field has a second homogeneity that is less homogenous than said first homogeneity;

a control computer configured to generate after making said division, a control protocol that incorporates the designation of said division, and to operate said magnetic resonance scanner to acquire magnetic resonance image data from the subject using an echo planar imaging sequence by, according to said designation of said division, acquiring magnetic resonance image data from said first selected section only from gradient echo signals in said echo planar imaging sequence and acquiring magnetic resonance image data from said second selected section from both gradient echo signals and spin echo signals in said echo planar imaging sequence; and

said control computer being configured to make the magnetic resonance image data from the subject available as an output from the control computer in a form allowing reconstruction of a visible image of the subject therefrom.

15. A system as claimed in claim 14 comprising an image reconstruction computer configured to reconstruct said visible image of the subject from said magnetic resonance data that are output from the control computer.

16. A system as claimed in claim 14 wherein said control computer is configured to designate said division in said planar section by placing said dividing line at a location of a predetermined homogeneity threshold in said planar section.

17. A system as claimed in claim 14 wherein said magnetic resonance data acquisition unit is configured to acquire said magnetic resonance data from the brain of the subject, and wherein said control computer is configured to designate said division in a sagittal section, as said planar section, through the brain of the subject.

18. A system as claimed in claim 17 wherein said control computer is configured to designate said division to divide the brain of the subject in said sagittal section into an upper selected region, closer to a top of the head of the subject, as said first selected section, and a lower selected region, farther from the top of the head of the subject, as said second selected section.

19. A system as claimed in claim 18 wherein said control computer is configured to designate said division with said upper selected region encompassing two-thirds of the brain of the subject in said sagittal section and with said lower selected region encompassing approximately one-third of the brain of the subject in said sagittal section.

20. A system as claimed in claim 14 wherein said control computer is configured to operate said magnetic resonance scanner according to said control protocol to acquire said magnetic resonance data from successive slices of the subject.

21. A system as claimed in claim 20 wherein said control computer is configured to generate an echo planar imaging sequence in said control protocol that comprises a 90°

focusing pulse, followed by a gradient echo readout gradient in which said gradient echo signal is read out, followed by a 180°

refocusing pulse, followed by a spin echo readout gradient in which said spin echo signal is read out, and to operate said magnetic resonance scanner according to said control protocol to execute a gradient echo loop comprising said 90°

focusing pulse and said gradient echo readout gradient to acquire said magnetic resonance data from said first selected section and to execute a dual echo loop, comprising said 90°

focusing pulse, said gradient echo readout gradient, said 180°

refocusing pulse, and said spin echo readout gradient, to acquire said magnetic resonance data from said second selected section.

22. A system as claimed in claim 14 wherein said control computer comprises an interface that allows manual designation of said division via said interface.

23. A system as claimed in claim 14 wherein said control computer is configured to execute an algorithm to automatically designate said division that places said dividing line in said planar section based on a magnetic field map in said planar section of said subject.

24. A system as claimed in claim 14 wherein said control computer is configured to generate said control protocol for functional magnetic resonance imaging of the brain of the human or animal subject, and to designate said division in a planar section through said brain dependent on voids in said brain that produce said first homogeneity of said basic magnetic field in said first selected section and said second homogeneity of said basic magnetic field in said second selected section.

25. A system as claimed in claim 14 wherein said control computer is configured to operate said magnetic resonance scanner to acquire magnetic resonance data from a plurality of slices in said human or animal subject using said echo planar imaging sequence, and to acquire said magnetic resonance data from said first selected section in a plurality of slices in said first section, and to acquire said magnetic resonance image data from said second selected section in a plurality of other slices in said second section.