In-situ tear sample collection and testing using a contact lens
First Claim
Patent Images
1. A contact lens, comprising:
- a substrate that forms at least part of a body of the contact lens, the contact lens having a concave surface and a convex surface opposite the concave surface, wherein the concave surface is configured to be removably mounted over a corneal surface of an eye;
a plurality of recesses formed within the substrate and each of the plurality of recesses having an opening in the convex surface of the contact lens, configured to collect tear fluid when the contact lens is worn, and wherein each of the plurality of recesses extend into the body of the contact lens perpendicular to a line tangent to the convex surface at a center point of the convex surface; and
at least one sensor disposed within the substrate configured to sense presence of an analyte in the collected tear fluid.
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Accused Products
Abstract
Apparatus, systems and methods employing contact lenses having one or more sensor that sense an analyte in tear fluid and one or more recesses that collect the tear fluid. In some aspects, a contact lens includes a substrate that forms at least part of a body of the contact lens and a recess formed within the substrate configured to collect tear fluid when the contact lens is worn. The contact lens further includes at least one sensor disposed within the substrate configured to sense presence of an analyte in the collected tear fluid.
175 Citations
19 Claims
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1. A contact lens, comprising:
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a substrate that forms at least part of a body of the contact lens, the contact lens having a concave surface and a convex surface opposite the concave surface, wherein the concave surface is configured to be removably mounted over a corneal surface of an eye; a plurality of recesses formed within the substrate and each of the plurality of recesses having an opening in the convex surface of the contact lens, configured to collect tear fluid when the contact lens is worn, and wherein each of the plurality of recesses extend into the body of the contact lens perpendicular to a line tangent to the convex surface at a center point of the convex surface; and at least one sensor disposed within the substrate configured to sense presence of an analyte in the collected tear fluid. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method comprising:
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collecting tear fluid in a plurality of cavities disposed within a body of a contact lens, the contact lens having a concave surface and a convex surface opposite the concave surface, wherein the concave surface is configured to be removably mounted over a corneal surface of an eye, and each of the plurality of cavities having an opening in the convex surface of the contact lens, and wherein each of the plurality of cavities extends into the body of the contact lens perpendicular to a line tangent to the convex surface at a center point of the convex surface; and detecting presence of at least one analyte in the collected tear fluid via at least one sensor located within the body of the contact lens. - View Dependent Claims (13, 14, 15, 16, 17)
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18. A contact lens, comprising:
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a plurality of tear fluid collection recesses formed in a substrate that forms at least part of a body of the contact lens, the contact lens having a concave surface and a convex surface opposite the concave surface, wherein the concave surface is configured to be removably mounted over a corneal surface of an eye; each of the plurality of recesses further having an opening in the convex surface of the contact lens and being configured to collect tear fluid when the contact lens is worn, and wherein each of the plurality of recesses extends into the body of the contact lens perpendicular to a line tangent to the convex surface at a center point of the convex surface; at least one sensor configured to sense presence of one or more analytes in the tear fluid; a processor configured to determine a concentration of the one or more analytes; and a transmitter configured to transmit information relating to the concentration of the one or more analytes to an external device. - View Dependent Claims (19)
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Specification