Redox polymers
First Claim
1. A method for monitoring a level of an analyte in a subject, the method comprising:
- positioning at least a portion of an analyte sensor into a skin of a subject, wherein the analyte sensor comprises;
a working electrode; and
a counter electrode,wherein the working electrode comprises;
a non-conductive base material;
a conductive layer disposed on the base material; and
reagent positioned on the conductive layer, the reagent comprising a polymeric transition metal complex comprising;
a transition metal complex comprising the formula;
2 Assignments
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Accused Products
Abstract
Novel transition metal complexes of iron, cobalt, ruthenium, osmium, and vanadium are described. The transition metal complexes can be used as redox mediators in enzyme based electrochemical sensors. In such instances, transition metal complexes accept electrons from, or transfer electrons to, enzymes at a high rate and also exchange electrons rapidly with the sensor. The transition metal complexes include at least one substituted or unsubstituted biimidazole ligand and may further include a second substituted or unsubstituted biimidazole ligand or a substituted or unsubstituted bipyridine or pyridylimidazole ligand. Transition metal complexes attached to polymeric backbones are also described.
40 Citations
20 Claims
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1. A method for monitoring a level of an analyte in a subject, the method comprising:
positioning at least a portion of an analyte sensor into a skin of a subject, wherein the analyte sensor comprises; a working electrode; and a counter electrode, wherein the working electrode comprises; a non-conductive base material; a conductive layer disposed on the base material; and reagent positioned on the conductive layer, the reagent comprising a polymeric transition metal complex comprising; a transition metal complex comprising the formula; - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
Specification