System and method for measuring fluidics in arteries

• US 9,320,493 B2
• Filed: 07/08/2014
• Issued: 04/26/2016
• Est. Priority Date: 07/08/2014
• Status: Active Grant

• Current Assignee: Nadarasa Visveshwara
• Original Assignee: Nadarasa Visveshwara
• Inventors: Visveshwara, Nadarasa
• Primary Examiner(s): Peng, Bo J
• Application Number:
  US14/326,034
• Publication Number:
  US 20160007969A1
• Time in Patent Office: 658 Days
• Field of Search: 604 20- 22, 604533-539
• US Class Current: 1/1
• CPC Class Codes: A61B 2503/045 Newborns, e.g. premature baby monitoring
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/150038 for blood from umbilical cord
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61B 8/06 Measuring blood flow measuring volume flow in general G01F, e.g. G01F1/66, G01F1/72; measuring speed of fluids in general G01P5/00
• CPC Class Codes: A61B 8/065 to determine blood output from the heart in general A61B5/029
• CPC Class Codes: A61B 8/0866 involving foetal diagnosis; pre-natal or peri-natal diagnosis of the baby
• CPC Class Codes: A61B 8/0891 for diagnosis of blood vessels
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/4416 related to combined acquisition of different diagnostic modalities, e.g. combination of ultrasound and X-ray acquisitions
• CPC Class Codes: A61B 8/445 Details of catheter construction
• CPC Class Codes: A61B 8/4477 using several separate ultrasound transducers or probes
• CPC Class Codes: A61B 8/4483 characterised by features of the ultrasound transducer
• CPC Class Codes: A61B 8/488 involving Doppler signals
• CPC Class Codes: A61B 8/5223 for extracting a diagnostic or physiological parameter from medical diagnostic data for algorithms to analyse biomedical images G06T7/0012

Abstract

An apparatus for performing measurements in an artery includes a Doppler catheter, comprising a Doppler transducer and a wire connected to the Doppler transducer; and an elongated catheter body having a conduit therein for housing the wire of the Doppler catheter. The body has a proximal end and a distal end; wherein the wire is movable in the conduit relative to the catheter body so that the Doppler transducer and the wire are capable of being threaded into said conduit at the proximal end after the distal end of the catheter has been inserted into the artery, until the Doppler transducer emerges outside the conduit at the distal end of said body for performing ultrasound measurements in the artery. Another embodiment employs at least an additional side transducer for measuring the cross-sectional dimension of the artery useful for computing blood flow.

Claims

1. An apparatus for performing measurements in an artery, comprising:

a Doppler catheter, including a Doppler transducer and a wire connected to the Doppler transducer, said Doppler catheter further comprising a first connector and a second connector, the first connector containing the wire; and

an elongated catheter body having a conduit therein for housing the wire of the Doppler catheter, said body having a proximal end and a distal end;

a third connector attached to the catheter body, said third connector shaped to mate with the first connector to form a stable connection between the catheter body and the Doppler catheter; and

a sleeve having a first position and a second position wherein, when in the first position, the sleeve encloses substantially all of the wire, save for a wire portion proximate to the Doppler transducer protectable by a cap, thus protecting the wire from an environment and, when in the second position, the sleeve does not enclose most of the wire and the wire passes into the conduit of the elongated catheter body;

wherein said wire and Doppler transducer are movable in the conduit through the stable connection between the proximal end and the distal end of the catheter body after the stable connection has been formed so that the Doppler transducer and the wire are capable of being threaded into said conduit at the proximal end through the stable connection after the distal end of the catheter has been inserted into the artery, until the Doppler transducer emerges outside the conduit at the distal end of said body for performing ultrasound measurements in the artery.

2. The apparatus of claim 1, said Doppler catheter having a distal end and a proximal end, said first connector being at a location away from the proximal end of the Doppler catheter, and said second connector located at the proximal end of the Doppler catheter.

3. The apparatus of claim 2, further comprising a sleeve connected to the first and second connectors, said sleeve enclosing said wire and protecting the wire from an environment when the wire is withdrawn from the conduit in the body.

4. The apparatus of claim 3, wherein said sleeve is shorter than the wire such that when the wire is withdrawn from the conduit in the body, the length of the sleeve limits the extent by which the wire is withdrawn from the conduit.

5. The apparatus of claim 2, further comprising a cap for connection to the first connector when the Doppler catheter is not connected to the catheter body, to enclose and protect the Doppler transducer.

6. The apparatus of claim 2, wherein the first connector centers the Doppler transducer when the Doppler transducer is inserted into the conduit of the catheter body.

7. The apparatus of claim 1, wherein the first connector permits the wire to be moved relative to the first connector and to be inserted into, or withdrawn from, the conduit through the stable connection.

8. The apparatus of claim 7, wherein when the Doppler transducer and the wire are threaded into said conduit at the proximal end of the body and through the stable connection and moved relative to the first connector towards the distal end of the catheter body, the Doppler transducer will emerge at the distal end of said body and outside the conduit for performing ultrasound measurements in the artery.

9. The apparatus of claim 1, the third connector being attached to the proximal end of the catheter body and containing a first port that permits the Doppler transducer and the wire to pass there through and inserted into the conduit, and a second port connected to the conduit to defines a clear path from the second port through the conduit from the distal end of the body to the proximal end of the body, said clear path enabling blood pressure in the artery to be monitored through the second port whether or not the Doppler transducer and the wire are in the conduit.

10. The apparatus of claim 9, said third connector having a distal end and a proximal end, a third port at the distal end of the third connector attached to the proximal end of the body, said first port being at a proximal end of the connector adapted to receive the Doppler transducer and the wire, and said second port being suitable for infusion of a substance to the artery, for retrieving blood samples, or for blood pressure monitoring.

11. The apparatus of claim 9, said third connector being Y-shaped.

12. The apparatus of claim 11, said second port located between the first and third ports.

13. The apparatus of claim 1, said elongated catheter body comprising a material firm enough to enable the body to be inserted into arteries, but flexible enough to bend along turns in the arteries as in an umbilical artery in newborns.

14. The apparatus of claim 1, said elongated catheter body comprising a material rigid enough to be placed in tandem or within cardiac assist devices.

15. The apparatus of claim 1, said catheter body comprising polyurethane or metal.

16. The apparatus of claim 1, said Doppler catheter further comprising at least one second transducer for measuring at least one cross-sectional dimension of the artery, and at least one second wire connected to the at least one second transducer.

17. The apparatus of claim 16, further comprising ground leads for the Doppler and second transducers and a housing containing said wires and ground leads, said ground leads connected to the housing.

18. An apparatus for performing measurements in an artery, comprising:

a Doppler catheter, including a Doppler transducer, a second transducer and wires connected to the Doppler transducer and the second transducer and a first connector;

an elongated catheter body having a conduit therein for housing the wire of the Doppler catheter, said body having a proximal end and a distal end;

a second connector attached to the catheter body, said second connector shaped to mate with the first connector to form a stable connection between the catheter body and the Doppler catheter; and

a sleeve having a first position and a second position wherein, when in the first position, the sleeve encloses substantially all of the wire, save for a wire portion proximate to the Doppler transducer protectable by a cap, thus protecting the wire from an environment and, when in the second position, the sleeve does not enclose most of the wire and the wire passes into the conduit of the elongated catheter body;

said Doppler catheter suitable of being inserted and withdrawn from a conduit through said stable connection in the elongated catheter body having the conduit therein for housing the wire of the Doppler catheter, said body having a proximal end and a distal end;

wherein said Doppler transducer and second transducer and the wires are movable in the conduit through the stable connection between the proximal end and the distal end of the catheter body after the stable connection has been formed so that the Doppler transducer, the second transducer and the wires are capable of being threaded through said stable connection into said conduit at the proximal end after the distal end of the catheter has been inserted into the artery, until the Doppler transducer and the second transducer emerge outside the conduit at the distal end of said body for performing ultrasound measurement in and measurement of a cross-sectional dimension of the artery.