Coated medical devices and methods of making and using same
First Claim
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1. A medical device for treating an aneurysm, comprising:
- a tubular member comprising a plurality of braided filaments, each of the filaments crossing another of the filaments at a respective crossing point, that form a sidewall and a plurality of pores in the sidewall that are sized to inhibit flow of blood through the sidewall into an aneurysm to a degree sufficient to lead to thrombosis and healing of the aneurysm when the tubular member is positioned in a blood vessel and adjacent to the aneurysm, the pores having an average pore size that is less than or equal to about 500 microns when the body is in the expanded state; and
an antithrombogenic material distributed over the tubular member wherein the pores are substantially free of webs formed by the material such that webs are present at fewer than 5% of the crossing points.
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Abstract
Coating methods and related devices are provided. Such devices can include stents. For example, the device can comprise a sidewall and a plurality of pores in the sidewall that are sized to inhibit flow of blood through the sidewall into an aneurysm to a degree sufficient to lead to thrombosis and healing of the aneurysm when the tubular member is positioned in a blood vessel and adjacent to the aneurysm. The device can also comprise an anti-thrombogenic coating distributed over at least a portion of the device such that the pores are substantially free of webs formed by the coating.
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Citations
28 Claims
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1. A medical device for treating an aneurysm, comprising:
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a tubular member comprising a plurality of braided filaments, each of the filaments crossing another of the filaments at a respective crossing point, that form a sidewall and a plurality of pores in the sidewall that are sized to inhibit flow of blood through the sidewall into an aneurysm to a degree sufficient to lead to thrombosis and healing of the aneurysm when the tubular member is positioned in a blood vessel and adjacent to the aneurysm, the pores having an average pore size that is less than or equal to about 500 microns when the body is in the expanded state; and an antithrombogenic material distributed over the tubular member wherein the pores are substantially free of webs formed by the material such that webs are present at fewer than 5% of the crossing points. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 26, 27, 28)
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12. A medical device for treating an aneurysm, comprising:
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a tubular body configured to be implanted in a blood vessel and comprising a plurality of braided filaments each crossing another of the filaments at a respective crossing point, the body being expandable to an expanded state for treatment of the aneurysm, the body having a first section for spanning the neck of the aneurysm and a plurality of pores located between the filaments, the pores in the first section having a first average pore size of less than about 500 microns when the body is in the expanded state; the first section having a substantially complete distribution of antithrombogenic material over the filaments; wherein the first section is substantially free of webs formed between the braided filaments by the antithrombogenic material such that webs are present at fewer than 5% of the crossing points. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25)
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Specification