Devices and methods for modulating medium delivery

• US 9,320,846 B2
• Filed: 03/15/2013
• Issued: 04/26/2016
• Est. Priority Date: 08/28/2012
• Status: Active Grant

• Current Assignee: Osprey Medical, Inc.
• Original Assignee: Osprey Medical, Inc.
• Inventors: Burns, Matthew M., Doan, Tuan M., Houfburg, Rodney L., Kaye, David M., Mans, Daniel R., Mortier, Todd J.
• Primary Examiner(s): Bosworth, Kami A
• Assistant Examiner(s): Shah, Nilay
• Application Number:
  US13/839,771
• Publication Number:
  US 20140066891A1
• Time in Patent Office: 1,138 Days
• US Class Current: 1/1
• CPC Class Codes: A61M 2025/0076 Unidirectional valves
• CPC Class Codes: A61M 2039/2413 designed to reduce and or shut-off the flow when a certain maximum flow limit is exceeded
• CPC Class Codes: A61M 2205/3331 Pressure; Flow
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/3337 Controlling, regulating pressure or flow by means of a valve by-passing a pump
• CPC Class Codes: A61M 2205/3341 stabilising pressure or flow to avoid excessive variation
• CPC Class Codes: A61M 2205/3344 Measuring or controlling pressure at the body treatment site
• CPC Class Codes: A61M 2205/3355 Controlling downstream pump pressure
• CPC Class Codes: A61M 2206/22 eliminating pulsatile flows, e.g. by the provision of a dampening chamber
• CPC Class Codes: A61M 2210/125 Heart
• CPC Class Codes: A61M 2210/127 Aorta
• CPC Class Codes: A61M 25/0075 Valve means
• CPC Class Codes: A61M 39/24 Check- or non-return valves
• CPC Class Codes: A61M 5/007 for contrast media
• CPC Class Codes: A61M 5/1413 Modular systems comprising interconnecting elements
• CPC Class Codes: A61M 5/14212 Pumping with an aspiration and an expulsion action
• CPC Class Codes: A61M 5/14216 Reciprocating piston type
• CPC Class Codes: A61M 5/145 using pressurised reservoirs, e.g. pressurised by means of pistons
• CPC Class Codes: A61M 5/16881 Regulating valves on-off valves, e.g. clamps A61M39/28
• CPC Class Codes: A61M 5/48 having means for varying, regulating, indicating or limiting injection pressure A61M5/142 takes precedence ; monitoring pressure in infusion systems A61M5/16854
• CPC Class Codes: A61M 5/482 : Varying injection pressure, e.g. by varying speed of injection
• CPC Class Codes: A61M 5/484 : Regulating injection pressure
• CPC Class Codes: A61M 5/488 : Limiting injection pressure
• CPC Class Codes: F04B 11/0033 : with a mechanical spring
• CPC Class Codes: G16H 20/10 : relating to drugs or medications, e.g. for ensuring correct administration to patients
• CPC Class Codes: G16H 20/17 : delivered via infusion or injection

Abstract

Devices, systems and methods for controlling, regulating, altering, transforming or otherwise modulating the delivery of a substance to a delivery site. The devices, systems and methods optimize the delivery of the substance to an intended site, such as a vessel, vascular bed, organ and/or other corporeal structures, while reducing inadvertent introduction or reflux substance to other vessels, vascular beds, organs, and/or other structures, including systemic introduction.

Claims

1. A method for controlling, regulating, altering, transforming or otherwise modulating fluid delivery of a fluid medium to a selected site within a patient'"'"'s body, the method comprising:

injecting the fluid medium from a syringe through a fluid delivery catheter to deliver the fluid medium to the selected site;

simultaneously employing a mechanical modulating mechanism disposed between the syringe and said delivery catheter, said mechanical modulating mechanism residing outside the patient'"'"'s body and comprising;

a medium reservoir, the medium reservoir including a chamber for receiving the fluid medium therein and at least one surface within the chamber capable of imparting a force on the fluid medium within the chamber; and

a manifold having a manifold lumen therethrough, wherein the manifold lumen includes;

a first medium port fluidly coupled to the syringe,

a second medium port fluidly coupled to the chamber of the medium reservoir, and

a third medium port fluidly coupled to the delivery catheter,

said mechanical modulating mechanism capable of altering a delivery of the fluid medium to the selected site so as to maintain a desired flow rate to the selected site within the patient'"'"'s body for a period of time.

2. The method of claim 1 wherein the desired flow rate is a function of opacity of the fluid medium.

3. The method of claim 1 wherein the desired flow rate is a function of a sensed parameter of the patient.

4. The method of claim 1 wherein the period of time is a function of a sensed parameter of the patient.

5. The method of claim 1 wherein the mechanical modulating mechanism comprises a one-way valve.

6. The method of claim 1 wherein the desired flow rate corresponds to a pressure range of the fluid medium within the chamber.

7. The method of claim 6 wherein the pressure range has a low threshold value, wherein when a pressure of the fluid medium within the chamber is below the low threshold value, no fluid medium flows from the chamber to the delivery catheter.

8. The method of claim 6 wherein the pressure range has a high threshold value, wherein when a pressure of the fluid medium within the chamber is above the high threshold value, the fluid medium flows from the chamber to a location other than the delivery catheter.

9. The method of claim 1 wherein the period of time is during a performance of a treatment procedure.

10. The method of claim 1 wherein the selected site is a blood vessel, the fluid medium is a contrast agent, and wherein the desired flow rate is sufficient to opacify the blood vessel.

11. The method of claim 1 wherein the selected site is a blood vessel, and wherein the desired flow rate is less than a blood flow rate in the blood vessel.

12. The method of claim 1 wherein the selected site is a blood vessel, and wherein the desired flow rate is related to a blood flow rate in the blood vessel.