Combination therapy including peripheral nerve field stimulation

• US 9,320,847 B2
• Filed: 04/24/2015
• Issued: 04/26/2016
• Est. Priority Date: 06/09/2005
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Rooney, Ethan A., Wahlstrand, Carl D., King, Gary W., Cross, Thomas E. Jr., Heruth, Kenneth T., Wacnik, Paul W., Evanson, Jeffrey S.
• Primary Examiner(s): Heller, Tammie K
• Application Number:
  US14/696,248
• Publication Number:
  US 20150224251A1
• Time in Patent Office: 368 Days
• US Class Current: 1/1
• CPC Class Codes: A61M 2205/054 with electrotherapy
• CPC Class Codes: A61M 5/14 Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: A61N 1/0531 Brain cortex electrodes
• CPC Class Codes: A61N 1/0534 Electrodes for deep brain stimulation
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/0553 Paddle shaped electrodes, e.g. for laminotomy
• CPC Class Codes: A61N 1/0558 Anchoring or fixation means therefor
• CPC Class Codes: A61N 1/36017 with leads or electrodes penetrating the skin
• CPC Class Codes: A61N 1/36021 for treatment of pain
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/37211 Means for communicating with stimulators
• CPC Class Codes: A61N 1/375 Constructional arrangements, e.g. casings

Abstract

Delivery of peripheral nerve field stimulation (PNFS) in combination with one or more other therapies is described. The other therapy delivered in combination with PNFS may be, for example, a different type of neurostimulation, such as spinal cord stimulation (SCS), or a drug. PNFS and the other therapy may be delivered simultaneously, in an alternating fashion, according to a schedule, and/or selectively, e.g., in response to a request received from a patient or clinician. A combination therapy that includes PNFS may be able to more completely address complex or multifocal pain than would be possible through delivery of either PNFS or other therapies alone. Further, the combination of PNFS with one or more other therapies may reduce the likelihood that neural accommodation will impair the perceived effectiveness PNFS or the other therapies.

Claims

1. A method for treating pain of a patient, the method comprising:

delivering peripheral nerve field stimulation from a medical device to a region of a body of the patient in which a patient experiences pain via at least one electrode implanted in the region; and

delivering at least one other therapy to the patient that treats pain in combination with the peripheral nerve field stimulation.

2. The method of claim 1, wherein delivering the at least one other therapy to the patient that treats pain in combination with the peripheral nerve field stimulation comprises delivering the at least one other therapy from the medical device to the patient that treats pain in combination with the peripheral nerve field stimulation.

3. The method of claim 1, wherein the medical device comprises a first medical device, and wherein delivering the at least one other therapy to the patient that treats pain in combination with the peripheral nerve field stimulation comprises delivering the at least one other therapy from a second medical device to the patient that treats pain in combination with the peripheral nerve field stimulation.

4. The method of claim 1, wherein the at least one electrode comprises at least one first electrode, and wherein delivering the at least one other therapy to the patient that treats pain in combination with the peripheral nerve field stimulation comprises delivering the at least one other therapy to the patient via at least one second electrode that treats pain in combination with the peripheral nerve field stimulation.

5. The method of claim 1, wherein the medical device is electrically coupled to the at least one electrode via a medical lead carrying the at least one electrode.

6. The method of claim 1, wherein the medical device comprises an implantable medical device implanted in the patient.

7. The method of claim 1, wherein delivering the at least one other therapy in combination with the peripheral nerve field stimulation comprises delivering another neurostimulation therapy to a different location of the patient via one or more electrodes in combination with the peripheral nerve field stimulation.

8. The method of claim 7, wherein delivering the another neurostimulation therapy comprises delivering at least one of peripheral nerve stimulation, deep brain stimulation, or cortical stimulation from the medical device in combination with the peripheral nerve field stimulation.

9. The method of claim 7, wherein delivering the another neurostimulation therapy in combination with the peripheral nerve field stimulation comprises delivering the another neurostimulation therapy and the peripheral nerve field stimulation according to at least one of different stimulation parameters or different duty cycles.

10. The method of claim 1, wherein delivering the at least one other therapy in combination with the peripheral nerve field stimulation comprises delivering at least one therapeutic agent from a medical device to the patient in combination with the peripheral nerve field stimulation.

11. A system for treating pain of a patient, the system comprising:

a medical device including a therapy delivery module configured to deliver a therapy to the patient;

at least one electrode configured to deliver the therapy from the medical device to the patient; and

a processor configured to control the delivery of the therapy to the patient from the medical device to the patient via the at least one electrode, wherein the therapy includes delivery of peripheral nerve field stimulation from the medical device to a region of a body of the patient in which the patient experiences pain via the at least one electrode implanted in the region, and delivery of at least one other therapy to the patient that treats pain in combination with the peripheral nerve field stimulation.

12. The system of claim 11, wherein the medical device is configured to deliver the at least one other therapy to the patient that treats pain in combination with the peripheral nerve field stimulation.

13. The system of claim 11, wherein the medical device comprises a first medical device, the system further comprising a second medical device configured to deliver the at least one other therapy to the patient that treats pain in combination with the peripheral nerve field stimulation.

14. The system of claim 11, wherein the at least one electrode comprises at least one first electrode, the system comprising at least one second electrode, wherein the processor is configured to control delivery of the at least one other therapy to the patient via the at least one second electrode in combination with the peripheral nerve field stimulation.

15. The system of claim 11, further comprising a medical lead carrying the at least one electrode, wherein the medical lead is configured to electrically couple the at least one electrode to the medical device to deliver the peripheral nerve field stimulation.

16. The system of claim 11, wherein the medical device comprises an implantable medical device configured to be implanted in the patient.

17. The system of claim 11, wherein the processor is configured to control delivery of another neurostimulation therapy to a different location of the patient via one or more electrodes in combination with the peripheral nerve field stimulation.

18. The system of claim 17, wherein the another neurostimulation therapy comprises delivering at least one of peripheral nerve stimulation, deep brain stimulation, or cortical stimulation from the medical device in combination with the peripheral nerve field stimulation.

19. The system of claim 17, wherein the processor is configured to control the delivery of the another neurostimulation therapy and the peripheral nerve field stimulation according to at least one of different stimulation parameters or different duty cycles.

20. The system of claim 11, wherein the processor is configured to control delivery of at least one therapeutic agent from a medical device to the patient in combination with the peripheral nerve field stimulation.