Endoscopic delivery of red/NIR light to the subventricular zone

• US 9,320,914 B2
• Filed: 03/03/2008
• Issued: 04/26/2016
• Est. Priority Date: 03/03/2008
• Status: Expired due to Fees

• Current Assignee: Depuy Synthes Products Incorporated (Johnson & Johnson)
• Original Assignee: Depuy Synthes Products Incorporated (Johnson & Johnson)
• Inventors: Toselli, Richard, Di Mauro, Thomas M., Fisher, Michael
• Primary Examiner(s): Rodriguez, Cris L
• Assistant Examiner(s): Mai, Hao D
• Application Number:
  US12/041,405
• Publication Number:
  US 20090222067A1
• Time in Patent Office: 2,976 Days
• Field of Search: 607/87, 607/100, 607 88- 92
• US Class Current: 1/1
• CPC Class Codes: A61N 2005/0612 using probes penetrating tissue; interstitial probes
• CPC Class Codes: A61N 2005/063 comprising light transmitting means, e.g. optical fibres
• CPC Class Codes: A61N 2005/0659 infrared
• CPC Class Codes: A61N 2005/0662 Visible light
• CPC Class Codes: A61N 2005/0663 Coloured light
• CPC Class Codes: A61N 5/0601 Apparatus for use inside the body
• CPC Class Codes: A61N 5/0622 Optical stimulation for exciting neural tissue
• CPC Class Codes: A61N 5/067 using laser light

Abstract

Endoscopic delivery of Red/NIR light to the Substantia Nigra to treat Parkinson'"'"'s Disease in order to raise the energy levels in the substantia nigra.

Claims

1. A method of treating a patient having a neurodegenerative disease, comprising the steps of:

a) selecting an optical wave guide having a proximal end portion and a distal end portion;

b) endoscopically implanting the distal end portion of the optical wave guide into a lateral ventricle of the patient, and

c) delivering light through the optical wave guide to irradiate at least a portion of a subventricular zone with an effective amount of light.

2. A method of treating stroke, comprising the steps of:

a) selecting a stroke patient, and

b) delivering a distal end portion of an optical wave guide into a lateral ventricle of the patient, and

c) irradiating through the optical wave guide at least a portion of a subventricular zone of the patient with an effective amount of red/NIR light.