Catheter guidance of external energy for renal denervation

• US 9,326,751 B2
• Filed: 11/14/2011
• Issued: 05/03/2016
• Est. Priority Date: 11/17/2010
• Status: Expired due to Fees

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Inventors: Hastings, Roger
• Primary Examiner(s): Le, Long V
• Assistant Examiner(s): Weatherby, Ellsworth
• Application Number:
  US13/295,182
• Publication Number:
  US 20120123243A1
• Time in Patent Office: 1,632 Days
• Field of Search: 600/411, 600/421, 600/424, 600/427
• US Class Current: 1/1
• CPC Class Codes: A61B 17/2202 the ultrasound transducer being inside patient's body at the distal end of the catheter
• CPC Class Codes: A61B 2017/00106 ultrasonic
• CPC Class Codes: A61B 2018/00404 Blood vessels other than those in or around the heart
• CPC Class Codes: A61B 2018/00434 Neural system
• CPC Class Codes: A61B 2018/00511 Kidney
• CPC Class Codes: A61B 2034/2051 Electromagnetic tracking systems
• CPC Class Codes: A61B 2034/2063 Acoustic tracking systems, e.g. using ultrasound
• CPC Class Codes: A61B 2090/378 using ultrasound
• CPC Class Codes: A61B 2090/3788 transmitter only
• CPC Class Codes: A61B 2090/3929 Active markers
• CPC Class Codes: A61B 2090/3958 emitting a signal
• CPC Class Codes: A61B 2090/3966 Radiopaque markers visible in an X-ray image
• CPC Class Codes: A61B 34/20 Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
• CPC Class Codes: A61B 6/032 Transmission computed tomography [CT]
• CPC Class Codes: A61B 8/0841 for locating instruments
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/445 Details of catheter construction
• CPC Class Codes: A61B 8/4488 the transducer being a phased array
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61N 2005/1051 using an active marker markers in general A61B90/39
• CPC Class Codes: A61N 2005/1058 : using ultrasound imaging
• CPC Class Codes: A61N 2007/003 : Destruction of nerve tissue
• CPC Class Codes: A61N 2007/0052 : using the same transducer for therapy and imaging
• CPC Class Codes: A61N 7/02 : Localised ultrasound hyperthermia hyperthermia in general A61F7/00

Abstract

An in vivo apparatus includes a flexible shaft having a proximal end, a distal end, and a length sufficient to access a patient'"'"'s renal artery relative to a percutaneous access location. An energy guide apparatus is provided at the distal end of the shaft and dimensioned for deployment within the renal artery. An ex vivo apparatus includes an arrangement configured to localize the energy guide apparatus within the renal artery, and an energy source configured to direct ablative energy to target tissue located a predetermined distance from the localized energy guide apparatus. The target tissue includes perivascular renal nerve tissue adjacent the renal artery.

Claims

1. An apparatus, comprising:

an in vivo apparatus comprising;

a flexible shaft having a proximal end a distal end; and

an energy guide apparatus provided at the distal end of the shaft and configured to generate a rotating energy beacon including a rotating magnetic field and a rotating beam of acoustic energy;

an ex vivo apparatus comprising;

a localizing arrangement configured to localize the energy guide apparatus within a renal artery, wherein the localizing arrangement is configured to;

sense the rotating magnetic field;

detect the rotating beam of acoustic energy; and

localize the energy guide apparatus using at least the sensed rotating magnetic field and the detected rotating beam of acoustic energy; and

an energy source configured to direct ablative energy to a position that is adjacent to and offset from the localized energy guide apparatus;

wherein the localizing arrangement comprises an array of ultrasound transducers configured to receive the rotating beam of acoustic energy and operable in a low-intensity imaging mode to generate an image of the energy guide apparatus; and

wherein the localizing arrangement is configured to localize the energy guide apparatus within the renal artery using at least the generated image.