Methods for deploying intraocular shunts

• US 9,326,891 B2
• Filed: 05/15/2013
• Issued: 05/03/2016
• Est. Priority Date: 11/15/2010
• Status: Active Grant

• Current Assignee: AqueSys, Inc. (Abbvie Incorporated)
• Original Assignee: AqueSys, Inc. (Abbvie Incorporated)
• Inventors: Horvath, Christopher, Romoda, Laszlo O., Grabner, Guenther, Reitsamer, Herbert A.
• Primary Examiner(s): MARCETICH, ADAM M
• Application Number:
  US13/895,170
• Publication Number:
  US 20130253406A1
• Time in Patent Office: 1,084 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 3/10 Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
• CPC Class Codes: A61B 34/76 Manipulators having means for providing feel, e.g. force or tactile feedback
• CPC Class Codes: A61F 2009/00891 Glaucoma
• CPC Class Codes: A61F 9/0008 Introducing ophthalmic products into the ocular cavity or retaining products therein putting in contact lenses A61F9/0061; introducing or retaining media in cavities of the body in general A61M31/00
• CPC Class Codes: A61F 9/0017 implantable in, or in contact with, the eye, e.g. ocular inserts
• CPC Class Codes: A61F 9/007 Methods or devices for eye surgery
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002
• CPC Class Codes: A61M 2210/0612 Eyes
• CPC Class Codes: A61M 27/002 Implant devices for drainage of body fluids from one part of the body to another intraocular A61F9/00781; middle ear A61F11/202

Abstract

The present invention generally relates to methods for deploying intraocular shunts without the use of an optical apparatus that contacts an eye, such as a goniolens. In certain embodiments, methods of the invention involve inserting into an eye a deployment device configured to hold an intraocular shunt, determining that a distal portion of the device is properly positioned within the eye without use of an optical apparatus that contacts the eye, and deploying the shunt from the device.

Claims

1. A method for deploying a shunt within an eye, the method comprising:

inserting into an eye a deployment device configured to hold an intraocular shunt;

determining, without use of an optical apparatus that contacts the eye, that a distal portion of the device is at a position at the anterior chamber angle of the eye; and

advancing, from the device at the position, the shunt into eye tissue.

2. The method according to claim 1, wherein the determining comprises advancing the device until a resistance against further advancement is encountered.

3. The method according to claim 1, wherein the advancing the shunt results in a flow path from the anterior chamber of the eye to an area of lower pressure.

4. The method according to claim 1, wherein the area of lower pressure is selected from the group consisting of:

intra-tenon'"'"'s space, the subconjunctival space, the episcleral vein, the suprachoroidal space, and Schlemm'"'"'s canal.

5. The method according to claim 1, wherein the inserting step comprises inserting the device through the cornea.

6. The method according to claim 1, wherein the optical apparatus is a goniolens.

7. The method according to claim 1, wherein the advancing occurs without use of an optical apparatus that contacts the eye.

8. The method according to claim 1, wherein the position is at the trabecular meshwork of the eye.

9. The method according to claim 1, wherein the eye tissue comprises sclera.

10. A method for deploying a shunt within an eye, the method comprising:

inserting into an eye a deployment device configured to hold an intraocular shunt;

advancing, without use of an optical apparatus that contacts the eye, the device until a protrusion on a distal end of a housing of the device contacts an anatomical structure at the anterior chamber angle of the eye, thereby providing resistance against further advancement of the device; and

advancing the shunt from the device into the eye.

11. The method according to claim 10, wherein a distal portion of the housing comprises a sleeve and a hollow shaft that is movable within the sleeve, and further comprising distally advancing the hollow shaft relative to the sleeve after the advancing the device until the protrusion contacts the anatomical structure.

12. The method according to claim 11, wherein the protrusion is formed integrally with a distal end of the sleeve.

13. The method according to claim 11, wherein the protrusion is connected to a distal end of the sleeve.

14. The method according to claim 11, wherein the protrusion surrounds the distal end of the sleeve.

15. The method according to claim 11, wherein the protrusion extends around only a portion of the sleeve.

16. The method according to claim 10, wherein the inserting step comprises inserting the device through the cornea.

17. A method, for treating an eye, comprising positioning an intraocular shunt in eye tissue, without use of an optical apparatus that contacts the eye, such that the shunt conducts fluid from the anterior chamber of the eye.

18. The method according to claim 17, wherein the positioning comprises inserting a deployment device, configured to hold the intraocular shunt, into the eye, and thereafter advancing the deployment device into the eye until an increased resistance against further advancement is encountered.

19. The method according to claim 18, wherein the inserting step comprises inserting the device through the cornea.

20. The method according to claim 17, wherein the positioning results in a flow path from the anterior chamber of the eye to a region of the eye having a lower pressure than has the anterior chamber.

21. The method according to claim 17, wherein the region is selected from the group consisting of:

intra-tenon'"'"'s space, the subconjunctival space, the episcleral vein, the suprachoroidal space, and Schlemm'"'"'s canal.

22. The method according to claim 17, wherein the optical apparatus is a goniolens.