Porous bioabsorbable implant

• US 9,327,061 B2
• Filed: 09/21/2009
• Issued: 05/03/2016
• Est. Priority Date: 09/23/2008
• Status: Active Grant

• Current Assignee: Senorx Incorporated (Becton, Dickinson & Co)
• Original Assignee: Senorx Incorporated (Becton, Dickinson & Co)
• Inventors: Govil, Amit, Jones, Michael L., Lubock, Paul
• Primary Examiner(s): Severson, Ryan J
• Assistant Examiner(s): Papeika, Rachel S
• Application Number:
  US12/586,449
• Publication Number:
  US 20100082102A1
• Time in Patent Office: 2,416 Days
• Field of Search: 623/23.72, 623/23.75, 623/23.76, 623/23.73, 606/151, 606/214, 606/215, 424/424, 424/425, 424/426, 424/443, 424/444, 424/449
• US Class Current: 1/1
• CPC Class Codes: A61F 2/0077 Special surfaces of prostheses, e.g. for improving ingrowth A61F2/30767 takes precedence
• CPC Class Codes: A61F 2/02 Prostheses implantable into the body closure means for urethra or rectum or for artificial body openings therefor A61F2/0004
• CPC Class Codes: A61L 2300/102 Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
• CPC Class Codes: A61L 2300/104 Silver, e.g. silver sulfadiazine
• CPC Class Codes: A61L 2300/44 Radioisotopes, radionuclides
• CPC Class Codes: A61L 27/54 Biologically active materials, e.g. therapeutic substances A61L27/227 takes precedence
• CPC Class Codes: A61L 27/56 Porous materials, e.g. foams or sponges
• CPC Class Codes: A61L 27/58 Materials at least partially resorbable by the body
• CPC Class Codes: A61L 31/146 Porous materials, e.g. foams or sponges
• CPC Class Codes: A61L 31/148 Materials at least partially resorbable by the body
• CPC Class Codes: A61L 31/18 Materials at least partially X-ray or laser opaque

Abstract

The bioabsorbable implant described has a porous body formed of bioabsorbable materials that have an in vivo life span of at least 2 weeks, preferably at least three weeks and not greater than 20 weeks, preferably no greater than ten weeks. The implant has a scaffolding structure which facilitates tissue in-growth and ultimately tissue replacement of the scaffolding structure. The implant has a radiopaque imaging agent at least at the exterior margins and an orientation plurality of radiopaque elements in the interior of implant. The implant preferably has three radiopaque elements within the interior that form a plane within the implant interior.

Claims

1. An implant for a body cavity, comprising a body formed of a bioabsorbable material having a porosity sufficient to ensure tissue in-growth before significant bio-absorption of the implant, a radiopaque imaging agent which facilitates imaging of exterior margins of the implant and an interior orientation marker comprised of a plurality of radiopaque elements spaced inwardly from the exterior margins of the implant to facilitate relative orientation between the implant and a radiation source, wherein the plurality of radiopaque elements include at least three radiopaque elements arranged to form a plane within the interior of the implant wherein the plurality of radiopaque elements consists of three radiopaque elements which are located at apices of an equilateral triangle within the interior of the implant to form the plane.