Automatic anode and cathode fractional control and location to selectively avoid dorsal root stimulation

• US 9,327,128 B2
• Filed: 10/28/2014
• Issued: 05/03/2016
• Est. Priority Date: 10/30/2013
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Ranu, Emarit A. S.
• Primary Examiner(s): Wieland, Robert N
• Application Number:
  US14/526,031
• Publication Number:
  US 20150119957A1
• Time in Patent Office: 553 Days
• Field of Search: 607/59
• US Class Current: 1/1
• CPC Class Codes: A61N 1/0553 Paddle shaped electrodes, e.g. for laminotomy
• CPC Class Codes: A61N 1/36021 for treatment of pain
• CPC Class Codes: A61N 1/3605 Implantable neurostimulators for stimulating central or peripheral nerve system
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36185 Selection of the electrode configuration
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means

Abstract

A therapeutic neurostimulation system configured for providing therapy to a patient. The neurostimulation system comprises a neurostimulation lead having an array of electrodes arranged along a longitudinal axis configured for being implanted along a spinal cord of a patient, a neurostimulation device configured for delivering electrical stimulation energy to active ones of the electrode array, and control/processing circuitry for instructing the neurostimulation device to configure an active electrode as a cathode, and two active electrodes longitudinally flanking and laterally offset from the cathode as anodes, selecting a ratio of stimulation amplitude values for the two anodes based on a known longitudinal location of the implanted neurostimulation lead relative to the spinal cord, and instructing the neurostimulation device to distribute the electrical stimulation energy between the two anodes in accordance with the selected stimulation amplitude value ratio.

Claims

1. A neurostimulation system, comprising:

a neurostimulation lead configured to be implanted along a spinal cord of a patient, the neurostimulation lead including a paddle having a longitudinal axis and an array of electrodes;

a neurostimulation device configured to deliver electrical stimulation energy to active ones of the electrode array; and

control/processing circuitry configured to;

instruct the neurostimulation device to configure an active one of the electrode array as a cathode, and two active ones of the electrode array longitudinally flanking and laterally offset from the cathode as anodes;

select a ratio of stimulation amplitude values for the two anodes based on a known longitudinal location of the implanted neurostimulation lead relative to the spinal cord; and

instruct the neurostimulation device to distribute the electrical stimulation energy between the two anodes in accordance with the selected stimulation amplitude value ratio.

2. The neurostimulation system of claim 1, wherein the neurostimulation device is configured to determine the known longitudinal location of the implanted neurostimulation lead relative to the spinal cord.

3. The neurostimulation system of claim 1, further comprising a user interface configured to receive user input defining the known longitudinal location of the implanted neurostimulation lead relative to the spinal cord.

4. The neurostimulation system of claim 1, wherein the control/processing circuitry is configured to:

select a first ratio of stimulation amplitude values for the two anodes if the known longitudinal location is in a cervical region of the spinal cord; and

select a second ratio of the stimulation amplitudes for the two anodes if the longitudinal location is in a thoracic region of the spinal cord,

wherein the first stimulation amplitude ratio is closer to unity than the second stimulation amplitude ratio.

5. The neurostimulation system of claim 4, wherein the control/processing circuitry is configured to determine the more rostral one of the two anodes and the more caudal one of the two anodes, and the stimulation amplitude value for the more rostral anode is greater than the stimulation amplitude value for the more caudal anode.

6. The neurostimulation system of claim 5, wherein the second stimulation amplitude ratio is at least two.

7. The neurostimulation system of claim 1, further comprising memory with a look-up table stored in the memory, the look-up table containing a plurality of different stimulation amplitude ratios and associated neurostimulation lead locations, wherein the control/processing circuitry is configured to select the stimulation amplitude ratio by matching the known longitudinal location of the neurostimulation lead relative to the spinal cord with one of the neurostimulation lead locations stored in the look-up table and selecting the stimulation amplitude ratio associated with the matched neurostimulation lead location.

8. The neurostimulation system of claim 1, wherein the control/processing circuitry configured to:

instruct the neurostimulation device to configure two other active ones of the electrode array longitudinally flanking and laterally offset from the cathode as anodes;

select another ratio of stimulation amplitude values for the two other anodes based on the known longitudinal location of the implanted neurostimulation lead relative to the spinal cord; and

instruct the neurostimulation device to distribute the electrical stimulation energy between the two other anodes in accordance with the other selected stimulation amplitude value ratio.

9. The neurostimulation system of claim 1, wherein the array of electrodes includes electrodes arranged in a plurality of columns extending along the longitudinal axis, the cathode is in a first one of the columns, and the two anodes are in a second one of the columns.

10. The neurostimulation system of claim 1, wherein the control/processing circuitry is contained within the neurostimulation device.

11. The neurostimulation system of claim 1, further comprising an external controller containing the control/processing circuitry.

12. An external controller for use with a neurostimulation device coupled to an array of electrodes arranged along a longitudinal axis of the spinal column of the patient, the external controller comprising:

a user interface configured to receive user input;

control/processing circuitry configured to generate a set of stimulation parameters in response to the user input, the stimulation parameter set including an electrode combination designating one of the electrodes as a cathode, and two electrodes longitudinally flanking and laterally offset from the cathode as anodes, the stimulation parameter set further including stimulation amplitude values for the two anodes, the stimulation amplitude values having a ratio based on a known longitudinal location of the implanted neurostimulation lead relative to the spinal cord; and

output circuitry configured for transmitting the stimulation parameter set to the neurostimulation device.

13. The external control device of claim 12, wherein the control/processing circuitry is configured to determine the known longitudinal location of the implanted neurostimulation lead relative to the spinal cord.

14. The external control device of claim 12, wherein the user interface is configured to receive additional user input defining the known longitudinal location of the implanted neurostimulation lead relative to the spinal cord.

15. The external control device of claim 12, wherein the control/processing circuitry is configured to:

select a first ratio of stimulation amplitude values for the two anodes if the longitudinal location is in a cervical region of the spinal cord; and

select a second ratio of the stimulation amplitudes for the two anodes if the longitudinal location is in a thoracic region of the spinal cord,

wherein the first stimulation amplitude ratio is closer to unity than the second stimulation amplitude ratio.

16. The external control device of claim 15, wherein the control/processing circuitry is configured to determine the more rostral one of the two anodes and the more caudal one of the two anodes, and the stimulation amplitude value for the more rostral anode is greater than the stimulation amplitude value for the more caudal anode.

17. The external control device of claim 12, further comprising memory storing a look-up table containing a plurality of different stimulation amplitude ratios and associated neurostimulation lead locations, wherein the control/processing circuitry is configured for selecting the stimulation amplitude ratio by matching the known longitudinal location of the neurostimulation lead relative to the spinal cord with one of the neurostimulation lead locations stored in the look-up table and selecting the stimulation amplitude ratio associated with the matched neurostimulation lead location.

18. The external control device of claim 12, wherein the electrode combination further designates two other electrodes longitudinally flanking and laterally offset from the cathode, the stimulation parameter set further including stimulation amplitude values for the two other anodes, the stimulation amplitude values having another ratio based on the known longitudinal location of the implanted neurostimulation lead relative to the spinal cord.

19. The external control device of claim 12, wherein the array of electrodes is arranged in a plurality of columns along the longitudinal axis of the spinal column of the patient, the cathode is in a first one of the columns as a cathode, and the two anodes are in a second one of the columns as anodes.

20. The external control device of claim 19,

wherein the user interface comprises a directional control device configured to receive the user input;

wherein the control/processing circuitry is configured to generate a series of sets of stimulation parameters in response to the user input, each of the stimulation parameter sets including an electrode combination designating one of the electrodes in the first electrode column as a cathode, and two electrodes longitudinally flanking the cathode in the second electrode column as anodes, the stimulation parameter set further including stimulation amplitude values for the two anodes, the stimulation amplitude values having a ratio based on a known longitudinal location of the implanted neurostimulation lead relative to the spinal cord; and

wherein the output circuitry is configured to transmit the stimulation parameter sets to the neurostimulation device.