Self-contained biological assay apparatus, methods, and applications
First Claim
1. A self-contained, biological assay apparatus, comprising:
- a housing;
a dispensing platform including a controllably-movable reagent dispensing system, disposed in the housing;
a reagent supply component disposed in the housing;
a pneumatic manifold removeably disposed in the housing in a space shared by the dispensing platform, removeably coupled to a microfluidic system having a fluidic transport layer and a plurality of reservoirs which are fluidly connected to said fluidic transport layer, wherein the fluidic transport layer, the reservoirs, and a test sample to be introduced into the fluidic transport layer are disposed in the housing in the space separate from the dispensing platform;
a pneumatic supply system removeably coupled to the pneumatic manifold in the housing in a space separate from the dispensing platform; and
a control system coupled to at least one of the dispensing platform and the pneumatic supply system, disposed in the housing,wherein the apparatus is characterized as a self-contained, fully automated biological assay-performing apparatus,further wherein the test sample, once introduced, is transported from a starting location in the fluidic transport layer to the analysis reservoir separately from any other samples and separately from the pneumatic manifold and the dispensing system.
2 Assignments
0 Petitions
Accused Products
Abstract
A self-contained, fully automated, biological assay-performing apparatus includes a housing; a dispensing platform including a controllably-movable reagent dispensing system, disposed in the housing; a reagent supply component disposed in the housing; a pneumatic manifold removably disposed in the housing in a space shared by the dispensing platform, removably coupled to a fluidic transport layer and a plurality of reservoirs, wherein the fluidic transport layer, the reservoirs, and a test sample to be introduced therein are disposed in the housing in the space separate from the dispensing platform; a pneumatic supply system removably coupled to the pneumatic manifold in the housing in a space separate from the dispensing platform; and a control system coupled to at least one of the dispensing platform and the pneumatic supply system, disposed in the housing.
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Citations
25 Claims
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1. A self-contained, biological assay apparatus, comprising:
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a housing; a dispensing platform including a controllably-movable reagent dispensing system, disposed in the housing; a reagent supply component disposed in the housing; a pneumatic manifold removeably disposed in the housing in a space shared by the dispensing platform, removeably coupled to a microfluidic system having a fluidic transport layer and a plurality of reservoirs which are fluidly connected to said fluidic transport layer, wherein the fluidic transport layer, the reservoirs, and a test sample to be introduced into the fluidic transport layer are disposed in the housing in the space separate from the dispensing platform; a pneumatic supply system removeably coupled to the pneumatic manifold in the housing in a space separate from the dispensing platform; and a control system coupled to at least one of the dispensing platform and the pneumatic supply system, disposed in the housing, wherein the apparatus is characterized as a self-contained, fully automated biological assay-performing apparatus, further wherein the test sample, once introduced, is transported from a starting location in the fluidic transport layer to the analysis reservoir separately from any other samples and separately from the pneumatic manifold and the dispensing system. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25)
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Specification