Detecting, quantifying, and/or classifying seizures using multimodal data
First Claim
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1. A medical device system for detecting an epileptic event based upon a patient'"'"'s cardiac signal and kinetic activity, comprising:
- a first sensor for detecting a cardiac signal indicative of a patient'"'"'s heart activity;
a second sensor for detecting a kinetic signal indicative of body movement of the patient; and
a medical device (MD) coupled to the patient'"'"'s body and operatively coupled to the first sensor and the second sensor;
the MD comprising;
a kinetic signal module for receiving the kinetic signal;
a cardiac signal module for receiving the cardiac signal;
a cardiac index module for determining at least one cardiac index from the cardiac signal, wherein said at least one cardiac index is selected from a heart rate, a heart rhythm, an EKG morphology feature, or an EKG wave interval;
a detection module for determining whether an epileptic event has occurred based on a change in the at least one cardiac index, wherein said change in said at least one cardiac index is selected from an increase in the patient'"'"'s heart rate;
a decrease in the patient'"'"'s heart rate;
or a change in said at least one heart rhythm, EKG morphology feature, or EKG wave interval; and
an action module for taking a further action based on said kinetic signal, wherein the further action is selected from confirming the detecting of the epileptic event, or not confirming the detecting of the epileptic event.
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Abstract
Methods, systems, and apparatus for detecting an epileptic event, for example, a seizure in a patient using a medical device. The determination is performed by providing an autonomic signal indicative of the patient'"'"'s autonomic activity; providing a neurologic signal indicative of the patient'"'"'s neurological activity; and detecting an epileptic event based upon the autonomic signal and the neurologic signal.
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Citations
23 Claims
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1. A medical device system for detecting an epileptic event based upon a patient'"'"'s cardiac signal and kinetic activity, comprising:
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a first sensor for detecting a cardiac signal indicative of a patient'"'"'s heart activity; a second sensor for detecting a kinetic signal indicative of body movement of the patient; and a medical device (MD) coupled to the patient'"'"'s body and operatively coupled to the first sensor and the second sensor;
the MD comprising;a kinetic signal module for receiving the kinetic signal; a cardiac signal module for receiving the cardiac signal; a cardiac index module for determining at least one cardiac index from the cardiac signal, wherein said at least one cardiac index is selected from a heart rate, a heart rhythm, an EKG morphology feature, or an EKG wave interval; a detection module for determining whether an epileptic event has occurred based on a change in the at least one cardiac index, wherein said change in said at least one cardiac index is selected from an increase in the patient'"'"'s heart rate;
a decrease in the patient'"'"'s heart rate;
or a change in said at least one heart rhythm, EKG morphology feature, or EKG wave interval; andan action module for taking a further action based on said kinetic signal, wherein the further action is selected from confirming the detecting of the epileptic event, or not confirming the detecting of the epileptic event. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A medical device system for detecting an epileptic event based upon a patient'"'"'s cardiac signal and kinetic activity, comprising:
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a first sensor for detecting a cardiac signal indicative of a patient'"'"'s heart activity; a second sensor for detecting a kinetic signal indicative of body movement of the patient; and a medical device (MD) coupled to the patient'"'"'s body and operatively coupled to the first sensor and the second sensor;
the MD comprising;a kinetic signal module for receiving the kinetic signal; a cardiac signal module for receiving the cardiac signal; a kinetic index module for determining at least one kinetic index from the kinetic signal, wherein said at least one kinetic index is selected from a body posture, a body position, a fall, a parameter derived from an accelerometer signal selected from a movement, a frequency per unit time, a time interval between movements, a movement direction in at least one plane, an acceleration, a velocity, a force, a parameter derived from an inclinometer signal, or a change in one or more of the foregoing; a detection module for determining whether an epileptic event has occurred based on a change in the at least one kinetic index; and an action module for taking a further action based on said cardiac signal, wherein the further action is selected from confirming the detecting of the epileptic event, or not confirming the detecting of the epileptic event. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16)
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17. A medical device system for detecting an epileptic event based upon a patient'"'"'s cardiac signal and kinetic activity, comprising:
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a first sensor for detecting a cardiac signal indicative of a patient'"'"'s heart activity; a second sensor for detecting a kinetic signal indicative of body movement of the patient; and a medical device (MD) coupled to the patient'"'"'s body and operatively coupled to the first sensor and the second sensor;
the MD comprising;a kinetic signal module for receiving the kinetic signal; a cardiac signal module for receiving the cardiac signal; a cardiac index module for determining at least one cardiac index from the cardiac signal, wherein said at least one cardiac index is selected from a heart rate, a heart rhythm, an EKG morphology feature, or an EKG wave interval; a first characterization module for characterizing the at least one cardiac index as either indicative of an epileptic event or not indicative of an epileptic event; a kinetic index module for determining at least one kinetic index from the kinetic signal, wherein said at least one kinetic index is selected from a body posture, a body position, a fall, a parameter derived from an accelerometer signal selected from a movement, a frequency per unit time, a time interval between movements, a movement direction in at least one plane, an acceleration, a velocity, a force, a parameter derived from an inclinometer signal, or a change in one or more of the foregoing; a second characterization module for characterizing the kinetic signal as either indicative of an epileptic event or not indicative of an epileptic event; and an epileptic event detection module for detecting an epileptic event based on both the cardiac signal and the kinetic signal being indicative of the epileptic event. - View Dependent Claims (18, 19, 20, 21, 22, 23)
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Specification