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Systems, processes and computer-accessible medium for providing hybrid flourescence and optical coherence tomography imaging

  • US 9,332,942 B2
  • Filed: 01/28/2008
  • Issued: 05/10/2016
  • Est. Priority Date: 01/28/2008
  • Status: Active Grant
First Claim
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1. An apparatus for obtaining information regarding at least one portion of a chosen biological target, comprising:

  • a catheter having proximal and distal ends and an axis and including a first channel and a second channel,wherein the first and second channels together are configured to transmit at least first, second, and third radiations,wherein said first channel includes a first optical waveguide and is configured to transmit through the distal ends towards the proximal end, the first radiation that includes one of a mechanical radiation and an optical radiation including fluorescent radiation, the first radiation generated within said biological target in response to absorption by said target of third radiation transmitted through catheter from the proximal end;

    wherein said second channel includes a second optical waveguide and is configured to transmit, from said biological target through the distal end towards the proximal end, the second radiation representing anatomical characteristics of said target and containing optical-computed-tomography (OCT) information;

    wherein each of the first and second channels is structured to deflect a radiation transmitted through such channel to cause said radiation to traverse a first portion of such channel along the axis and a second portion of such channel along a line that is transverse to the axis;

    wherein said first optical waveguide dimensioned to channel only the first radiation and the second optical waveguide is dimensioned to channel only the second radiation;

    wherein the catheter is configured to outcouple said first and second radiations from the first and second optical waveguides at respectively corresponding first and second locations,wherein the first location is defined at an outer surface of the first optical waveguide away from an output facet of the first optical waveguide at a proximal end thereof, the second location defined at an output facet of the second optical waveguide at a proximal end thereof,anda detector operably connected with the proximal end to acquire radiation energy and to produce output data representing said target, said output data including a first data portion representing the first radiation and a second data portion representing the second radiation.

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