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Method for treating the ear, nose, sinus or throat

  • US 9,333,220 B2
  • Filed: 11/13/2013
  • Issued: 05/10/2016
  • Est. Priority Date: 04/24/2008
  • Status: Active Grant
First Claim
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1. A method for treating bodily tissue or structure in the ear, nose, sinus or throat, which method comprises:

  • a) applying to such ear, nose, sinus or throat tissue or structure a fluid layer containing a mixture of (i) chitosan having a number average molecular weight before sterilization of at least about 50 kDa and (ii) an oxidized polysaccharide, andb) allowing the mixture to crosslink in situ to form a protective gel layer that remains exposed to air or other nearby gases, reduces adhesions to anatomy, and has a residence time of one day to four weeks.

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