Automated diagnostic analyzers having rear accessible track systems and related methods

• US 9,335,338 B2
• Filed: 03/14/2014
• Issued: 05/10/2016
• Est. Priority Date: 03/15/2013
• Status: Active Grant

• Current Assignee: Abbott Laboratories Incorporated, Toshiba Medical Systems Corporation (Canon Inc.)
• Original Assignee: Abbott Laboratories Incorporated, Toshiba Medical Systems Corporation (Canon Inc.)
• Inventors: Arnquist, David C., Oonuma, Takehiko, Tahara, Hirotoshi, Sato, Naoto, Ochranek, Brian L., Smith, Bradley P.
• Primary Examiner(s): Mui, Christine T
• Application Number:
  US14/213,048
• Publication Number:
  US 20140273242A1
• Time in Patent Office: 788 Days
• Field of Search: 436/47, 436/43, 422/65, 422/64, 422/63
• US Class Current: 1/1
• CPC Class Codes: G01N 2035/0406 Individual bottles or tubes
• CPC Class Codes: G01N 33/5302 Apparatus specially adapted for immunological test procedures
• CPC Class Codes: G01N 35/00732 Identification of carriers, materials or components in automatic analysers
• CPC Class Codes: G01N 35/02 using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations G01N35/0098 and G01N35/0099 take precedence
• CPC Class Codes: G01N 35/025 having a carousel or turntable for reaction cells or cuvettes
• CPC Class Codes: G01N 35/04 Details of the conveyor system G01N35/021 - G01N35/028 take precedence
• CPC Class Codes: G01N 35/10 Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices G01N35/0099 takes precedence
• CPC Class Codes: Y10T 436/11 Automated chemical analysis
• CPC Class Codes: Y10T 436/113332 with conveyance of sample along a test line in a container or rack

Abstract

Example apparatus and methods related to automated diagnostic analyzers having rear accessible track systems. An example apparatus disclosed herein includes an analyzer to perform a diagnostic test, the analyzer having a first side and a second side opposite the first side. The example apparatus includes a loading bay disposed on the first side of the analyzer to receive a first carrier and a pipetting mechanism coupled to the analyzer adjacent the second side. The example apparatus also includes a first carrier shuttle to transport the first carrier from a first location adjacent the loading bay to a second location adjacent the pipetting mechanism and a track disposed adjacent the second side of the analyzer to transfer a second carrier to a third location adjacent the pipetting mechanism.

Claims

1. An apparatus comprising:

an analyzer to perform a diagnostic test, the analyzer having a first side and a second side opposite the first side;

a loading bay disposed on the first side of the analyzer to receive a first carrier;

a pipetting mechanism coupled to the analyzer adjacent the second side;

a first carrier shuttle to transport the first carrier from a first location adjacent the loading bay to a second location adjacent the pipetting mechanism; and

a track disposed adjacent the second side of the analyzer to transfer a second carrier to a third location adjacent the pipetting mechanism.

2. The apparatus of claim 1 further comprising a second carrier shuttle, wherein the loading bay is to receive a third carrier and the second carrier shuttle is to transport the third carrier from the first location adjacent the loading bay to the second location adjacent the pipetting mechanism.

3. The apparatus of claim 2, wherein the first carrier shuttle and the second carrier shuttle are independently movable.

4. The apparatus of claim 2 further comprising a positioner to transport the first carrier from a slot in the loading bay to the first carrier shuttle.

5. The apparatus of claim 4, wherein the positioner is to transport the third carrier from a slot in the loading bay to the second carrier shuttle.

6. The apparatus of claim 1, wherein the first carrier shuttle comprises a lead screw.

7. The apparatus of claim 1, wherein the first carrier shuttle comprises a conveyor belt.

8. The apparatus of claim 1, wherein the first carrier shuttle is to move in a direction substantially perpendicular to the track.

9. The apparatus of claim 1, wherein the track comprises a spur to transport the second carrier to or from the third location.

10. The apparatus of claim 1 further comprising a motor to operate the first carrier shuttle, wherein the motor is disposed at one of the first location or the second location.

11. The apparatus of claim 10 further comprising a sensor to detect movement in the first carrier shuttle, wherein the sensor is disposed at the other of the first location or the second location, opposite the motor.

12. The apparatus of claim 1, wherein the analyzer comprises a rotatable plate having a plurality of reaction vessels, and wherein the pipetting mechanism is to dispense liquid into one or more of the reaction vessels.

13. The apparatus of claim 12, wherein the pipetting mechanism is to follow a first protocol of liquid transfer between at least one of the second location or the third location and the reaction vessels.

14. The apparatus of claim 13, wherein the first protocol is to be suspended, the first carrier shuttle or a second carrier is shuttle to transport a third carrier from the loading bay to the second location, and the pipetting mechanism is to transfer liquid between the third carrier and at least one of the reaction vessels.

15. The apparatus of claim 1, wherein the pipetting mechanism is to at least one of dispense or aspirate a sample from the second location and the third location.

16. A method comprising:

transporting a first carrier from a first side of an analyzer having a loading bay to a second side of the analyzer opposite the first side;

aspirating a first liquid from the first carrier using a pipetting mechanism disposed adjacent the second side of the analyzer;

dispensing the first liquid, via the pipetting mechanism, into a first vessel on the analyzer;

transporting a second carrier along a track to a position adjacent the pipetting mechanism, the track disposed along the second side of the analyzer;

aspirating a second liquid from the second carrier using the pipetting mechanism; and

dispensing the second liquid, via the pipetting mechanism, into a second vessel on the analyzer.

17. The method of claim 16, wherein the first carrier is transported to the second side of the analyzer via a first carrier shuttle.

18. The method of claim 17 further comprising transporting a third carrier from the first side of the analyzer to the second side of the analyzer.

19. The method of claim 18 further comprising:

aspirating a third liquid from the third carrier using the pipetting mechanism; and

dispensing the third liquid, via the pipetting mechanism, into a third vessel on the analyzer.

20. The method of claim 18, wherein the third carrier is transported to the second side of the analyzer via a second carrier shuttle.

21. The method of the claim 20, wherein the first carrier shuttle and the second carrier shuttle operate independently of each other.

22. The method of claim 20, wherein one or more of the first carrier shuttle or the second carrier shuttle is a track comprising a lead screw.

23. The method of claim 20, wherein one or more of the first carrier shuttle or the second carrier shuttle is a track comprising a conveyor belt.

24. The method of claim 18, wherein one or more of the first carrier, the second carrier or the third carrier comprises at least one test sample tube.

25. The method of claim 17 further comprising transporting the first carrier from the loading bay on the first side of the analyzer to the first carrier shuttle.

26. The method of claim 25, wherein the first carrier is transported from the loading bay to the first carrier shuttle via a positioner.

27. A system comprising:

a first analyzer to perform a first diagnostic test, the first analyzer comprising;

a first proximal side and a first distal side opposite the first proximal side;

a first pipetting mechanism adjacent the first distal side;

a first loading bay disposed on the first proximal side to receive a first carrier; and

a first carrier shuttle to transport the first carrier from a first location adjacent the first proximal side to a second location adjacent the first pipetting mechanism;

a second analyzer disposed adjacent the first analyzer, the second analyzer to perform a second diagnostic test, the second analyzer comprising;

a second proximal side and a second distal side opposite the second proximal side;

a second pipetting mechanism adjacent the second distal side;

a second loading bay disposed on the second proximal side to receive a second carrier; and

a second carrier shuttle to transport the second carrier from a third location adjacent the second proximal side of the second analyzer to a fourth location adjacent the second pipetting mechanism; and

a track disposed along the first distal side and the second distal side, the track comprising a first sidetrack to transfer a third carrier to a fifth location adjacent the first pipetting mechanism.

28. The system of claim 27, wherein the track further comprises a second sidetrack to transfer the third carrier to a sixth location adjacent the second pipetting mechanism.

29. The system of claim 27, wherein the first carrier shuttle and the second carrier shuttle are substantially parallel.

30. The system of claim 29, wherein the first carrier shuttle is substantially perpendicular to the track.

31. The system of claim 27, wherein the first diagnostic test is an immunoassay and the second diagnostic test is a clinical chemistry assay.

32. The system of claim 27, wherein the first diagnostic test is an immunoassay and the second diagnostic test is an immunoassay.

33. The system of claim 27, wherein the first diagnostic test is a clinical chemistry assay and the second diagnostic test is a clinical chemistry assay.

34. The system of claim 27 further comprising a positioner disposed along the first proximal side of the first analyzer and the second proximal side of the second analyzer.

35. The system of claim 34, wherein the positioner is to transfer the second carrier from the second loading bay to the first carrier shuttle on the first analyzer.

36. The system of claim 27 further comprising a third analyzer disposed next to one of the first analyzer or the second analyzer, the third analyzer comprising:

a third proximal side and a third distal side opposite the third proximal side;

a third pipetting mechanism adjacent the third distal side;

a third loading bay disposed on the third proximal side to receive a fourth carrier; and

a third carrier shuttle to transport the fourth carrier from a sixth location adjacent the third proximal side of the third analyzer to a seventh location adjacent the third pipetting mechanism.

37. The system of claim 36, wherein the track is disposed along the third distal side of the third analyzer.