Vascular implant and delivery system
First Claim
1. A replacement mitral valve configured to be delivered to a native mitral valve and secured relative to a native mitral valve annulus, the native mitral valve positioned between a left atrium and a left ventricle, the replacement mitral valve comprising:
- an expandable frame comprising a proximal end and a distal end and having a longitudinal axis extending between the proximal end and the distal end, the expandable frame configured to radially expand and contract for deployment within the native mitral valve;
a first anchoring portion configured to at least partially engage an atrial side of the native mitral valve annulus, the first anchoring portion comprising a plurality of circumferentially-spaced tips connected by at least one row of circumferentially expansible elements extending continuously around the first anchoring portion, wherein when the expandable frame is in an expanded configuration, the first anchoring portion extends radially outwardly from a portion of the expandable frame that has a first cross-sectional dimension such that the at least one row of circumferentially expansible elements has a second cross-sectional dimension greater than the first cross-sectional dimension;
a second anchoring portion distal to the first anchoring portion and comprising a plurality of anchors extending from the expandable frame configured for placement on a ventricular side of the native mitral valve annulus, wherein when the expandable frame is in an expanded configuration, the plurality of anchors extend at least partially proximally toward the first anchoring portion; and
a valve body connected to the expandable frame;
wherein radial expansion of the expandable frame causes the first anchoring portion and the second anchoring portion to draw closer together; and
wherein, when the expandable frame is in the expanded configuration, tips of the plurality of anchors of the second anchoring portion extend to a third cross-sectional dimension which is at least about the same as the second cross-sectional dimension.
3 Assignments
0 Petitions
Accused Products
Abstract
A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant can be verified prior to full release. The implant can be at least partially resheathed and repositioned if desired.
957 Citations
29 Claims
-
1. A replacement mitral valve configured to be delivered to a native mitral valve and secured relative to a native mitral valve annulus, the native mitral valve positioned between a left atrium and a left ventricle, the replacement mitral valve comprising:
-
an expandable frame comprising a proximal end and a distal end and having a longitudinal axis extending between the proximal end and the distal end, the expandable frame configured to radially expand and contract for deployment within the native mitral valve; a first anchoring portion configured to at least partially engage an atrial side of the native mitral valve annulus, the first anchoring portion comprising a plurality of circumferentially-spaced tips connected by at least one row of circumferentially expansible elements extending continuously around the first anchoring portion, wherein when the expandable frame is in an expanded configuration, the first anchoring portion extends radially outwardly from a portion of the expandable frame that has a first cross-sectional dimension such that the at least one row of circumferentially expansible elements has a second cross-sectional dimension greater than the first cross-sectional dimension; a second anchoring portion distal to the first anchoring portion and comprising a plurality of anchors extending from the expandable frame configured for placement on a ventricular side of the native mitral valve annulus, wherein when the expandable frame is in an expanded configuration, the plurality of anchors extend at least partially proximally toward the first anchoring portion; and a valve body connected to the expandable frame; wherein radial expansion of the expandable frame causes the first anchoring portion and the second anchoring portion to draw closer together; and wherein, when the expandable frame is in the expanded configuration, tips of the plurality of anchors of the second anchoring portion extend to a third cross-sectional dimension which is at least about the same as the second cross-sectional dimension. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
-
-
14. A replacement mitral valve configured to be delivered to a native mitral valve and secured relative to a native mitral valve annulus, the native mitral valve positioned between a left atrium and a left ventricle, the replacement mitral valve comprising:
-
an expandable frame extending along a longitudinal axis between a first end and a second end, the expandable frame comprising a first portion and a second portion, the first portion being closer to the first end than the second portion is to the first end, and the second portion being closer to the second end than the first portion is to the second end, wherein the second portion comprises a plurality of foreshortening cells and the first portion comprises a plurality of struts having at least a portion thereof extending longitudinally from foreshortening cells of the second portion toward the first end of the expandable frame, wherein the first portion comprises a non-foreshortening portion that does not substantially foreshorten when the expandable frame is radially expanded; a plurality of anchors connected to the second portion of the expandable frame, wherein the plurality of anchors extend radially outward from the expandable frame and extend in a direction generally toward the first end when the expandable frame is in an expanded configuration; and a valve body attached to the expandable frame; wherein when the expandable frame is in an expanded configuration, the first portion comprises an anchoring portion configured to engage an atrial side of the native mitral valve annulus that extends radially outwardly from the second portion in a direction generally perpendicular to the longitudinal axis, and wherein the replacement mitral valve is shaped such that, after the replacement mitral valve has been delivered to the native mitral valve and expanded, at least a portion of the anchoring portion contacts tissue on the atrial side of the native mitral valve annulus and at least some of the plurality of anchors contact tissue on the ventricular side of the native mitral valve annulus. - View Dependent Claims (15, 16, 17, 18, 19)
-
-
20. A replacement mitral valve configured to be delivered to a native mitral valve and secured relative to a native mitral valve annulus, the native mitral valve positioned between a left atrium and a left ventricle, the replacement mitral valve comprising:
-
an expandable frame comprising a proximal end and a distal end and having a longitudinal axis extending between the proximal end and the distal end, the expandable frame configured to radially expand and contract for deployment within the native mitral valve; a first anchoring portion sized to at least partially engage an atrial side of the native mitral valve annulus, wherein when the expandable frame is in an expanded configuration; a first section of the first anchoring portion extends radially outwardly of the longitudinal axis and at least partially proximally; and a second section of the first anchoring portion proximal to the first section extends radially inwardly from the first section towards the longitudinal axis and at least partially proximally; a second anchoring portion distal to the first anchoring portion and comprising a plurality of anchors extending from the expandable frame sized for placement on a ventricular side of the native mitral valve annulus, wherein when the expandable frame is in an expanded configuration, the plurality of anchors extend at least partially proximally toward the first anchoring portion; and a valve body connected to the expandable frame. - View Dependent Claims (21, 22, 23, 24, 25, 26, 27, 28, 29)
-
Specification